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Analgesic and Anti Inflammatory Activities of Ctenolepis garcinii (burm. f)


Affiliations
1 Department of Pharmacology, Sankaralingham Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi-626130, India
2 Department of Phamacognosy, Sankaralingham Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi-626130, India
     

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The anti inflammatory effects of Methanolic extract of Ctenolepis garcinii (burm. f) was assessed by carrageenan induced rat paw edema at the doses of 100 and 200 mg/kg p.o. The Methanolic extract 200 mg/kg p.o. shows significant and maximum activity, whose potency is less than the standard Diclofenac sodium. At the same dose, the analgesic activity was also assessed by Tail immersion method, The Methanolic extract of 200 mg/kg p.o. shows increased in the time of tail withdrawal response, which activity is significant as compared to the Standard Diclofenac sodium.

Keywords

Ctenolepis garcinii (burm.f), Analgesic, Anti Inflammatory, Methanolic Extract, Diclofenac Sodium.
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  • Analgesic and Anti Inflammatory Activities of Ctenolepis garcinii (burm. f)

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Authors

P. Natarajan
Department of Pharmacology, Sankaralingham Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi-626130, India
A. Thanga Thirupati
Department of Pharmacology, Sankaralingham Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi-626130, India
R. Sutharsingh
Department of Phamacognosy, Sankaralingham Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi-626130, India
J. Immanuvel Manicaraj
Department of Pharmacology, Sankaralingham Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi-626130, India
N. Vijayakrishnan
Department of Pharmacology, Sankaralingham Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi-626130, India

Abstract


The anti inflammatory effects of Methanolic extract of Ctenolepis garcinii (burm. f) was assessed by carrageenan induced rat paw edema at the doses of 100 and 200 mg/kg p.o. The Methanolic extract 200 mg/kg p.o. shows significant and maximum activity, whose potency is less than the standard Diclofenac sodium. At the same dose, the analgesic activity was also assessed by Tail immersion method, The Methanolic extract of 200 mg/kg p.o. shows increased in the time of tail withdrawal response, which activity is significant as compared to the Standard Diclofenac sodium.

Keywords


Ctenolepis garcinii (burm.f), Analgesic, Anti Inflammatory, Methanolic Extract, Diclofenac Sodium.

References