Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Analgesic and Anti Inflammatory Activities of Ctenolepis garcinii (burm. f)


Affiliations
1 Department of Pharmacology, Sankaralingham Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi-626130, India
2 Department of Phamacognosy, Sankaralingham Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi-626130, India
     

   Subscribe/Renew Journal


The anti inflammatory effects of Methanolic extract of Ctenolepis garcinii (burm. f) was assessed by carrageenan induced rat paw edema at the doses of 100 and 200 mg/kg p.o. The Methanolic extract 200 mg/kg p.o. shows significant and maximum activity, whose potency is less than the standard Diclofenac sodium. At the same dose, the analgesic activity was also assessed by Tail immersion method, The Methanolic extract of 200 mg/kg p.o. shows increased in the time of tail withdrawal response, which activity is significant as compared to the Standard Diclofenac sodium.

Keywords

Ctenolepis garcinii (burm.f), Analgesic, Anti Inflammatory, Methanolic Extract, Diclofenac Sodium.
Subscription Login to verify subscription
User
Notifications
Font Size


  • L. Bohlin. Structure-activity studies of natural products with anti-inflammatory effects. In: Hostettmann, K. (Ed.). Analgesic Activities of Cussonia paniculata. Phytochemistry of Plants used in Traditional Medicine. Clarendon Press, Oxford. 52;1995: 137-161
  • E. Yesilada, O. Ustun, E. Sezik, Y. Takishi, Y. Ono and G. Honda . Inhibitory effects of Turkish folk remedies on inflammatory cytokines: interleukin-1α, interleukin- 1β and tumor necrosis factor-α. J Ethnopharmacol. 58; 1997: 59-73
  • R. W. Li, S. P. Myers, D. N. Leach, G. D. Lin, G. Leach. A cross-cultural study: anti-inflammatory activity of Australian and Chinese plants. J Ethnopharmacol. 85; 2003: 25-32
  • J. R. Vane and R. M. Bolting. New insights into the mode of action of anti inflammatory drugs. Inflammation Res. 44; 1995: 1-10
  • J. B. Perianayagam, S. K. Sharma and K. K. Pillai . Anti-inflammatoryactivity of Trichodesma Indicum ischolar_main extract in experimental animals. J Ethnopharmacol.104; 2006: 410-414
  • J. R. Dharmasiri, A. C. Jayakody, G. Galhena, S. S. P. Liyanage and W. D. Ratnasooriya. Anti-inflammatory and analgesic activities of mature fresh leaves of Vitex Negundo. J Ethnopharmacol. 87; 2003: 199-206
  • J. H. Park, K. H. Son, S. W. Kim, H. W. Chang, K. Bae, S. S. Kang, H. P. Kim . Anti-inflammatory activity of Synurus deltoids. Phytother Res.18; 2004: 930-933
  • N. K. V. M. R. Kumara. Identification of strategies to improve research on medicinal plants used in Sri Lanka. In: WHO Symposium. University of Ruhuna, Galle, Sri Lanka. 12-14
  • P.N. Behl and G. Srivastava. HERBS useful
  • in Dermatological theraphy, Edited by P.N. Behl and G. Srivastava, CBS Publishers, New Delhi. 2002; 2nd ed: pp.1
  • Dr. S.H. Ansari. Essential of Pharmacognosy, Edited by Dr.S.H. Ansari, Birla publications, New Delhi. 2007-2008, 2nd ed: pp.719
  • Clinical Pharmacology by Dr.Laurence, P.N.Bennett,. 7th edition, Pg.No.229-231 a. Donald g. payan, MD & Bectram G. Katzung, MD, phD. Nonsteroidal anti inflammatory drugs; Non-opiod Analgesics; Drugs used in Gout in Bectram G. Katzung. Basic and clinical Pharmacology; Edited by Bectrum G. Katzung, MD phD. 25 Van zant streets, East Norwalk 1995; 6th ed: pp. 536.
  • Gavimath C.C, Kangralkar V.A, Shanmuga apriya V.G and Rameshwari kundargi. Evaluation of Anti bacterial and anti inflammatory potentials of essential oil of Citrus Reticulata. Advances in pharmacology and toxicology.10 (3); 2009: 31-34
  • Schweinf.Beitr. Z. fl. Aeth, zehneria cerasiformis stocks in hook. Bryonia fimbristipula fenzl in flora Journ. of bot. and key. Gard. Misc.1852: 312
  • D.Mridha, D, saha and P.A.DAS; Analgesic activity of the bark parkinsonia Aculeata. Advances in Pharmacology and Toxicology.11 (1); 2010: 91-94
  • Chakrabarthy A., Devi R.K.B., Sharatchandra K.H., Singh T., preliminary, studies on anti inflammatory and analgesics activities of Spilanthes Acemella in experimental animal models. Indian journal of pharmacology.36 (3); 2004: 148-150

Abstract Views: 364

PDF Views: 0




  • Analgesic and Anti Inflammatory Activities of Ctenolepis garcinii (burm. f)

Abstract Views: 364  |  PDF Views: 0

Authors

P. Natarajan
Department of Pharmacology, Sankaralingham Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi-626130, India
A. Thanga Thirupati
Department of Pharmacology, Sankaralingham Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi-626130, India
R. Sutharsingh
Department of Phamacognosy, Sankaralingham Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi-626130, India
J. Immanuvel Manicaraj
Department of Pharmacology, Sankaralingham Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi-626130, India
N. Vijayakrishnan
Department of Pharmacology, Sankaralingham Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi-626130, India

Abstract


The anti inflammatory effects of Methanolic extract of Ctenolepis garcinii (burm. f) was assessed by carrageenan induced rat paw edema at the doses of 100 and 200 mg/kg p.o. The Methanolic extract 200 mg/kg p.o. shows significant and maximum activity, whose potency is less than the standard Diclofenac sodium. At the same dose, the analgesic activity was also assessed by Tail immersion method, The Methanolic extract of 200 mg/kg p.o. shows increased in the time of tail withdrawal response, which activity is significant as compared to the Standard Diclofenac sodium.

Keywords


Ctenolepis garcinii (burm.f), Analgesic, Anti Inflammatory, Methanolic Extract, Diclofenac Sodium.

References