Research Journal of Pharmacology and Pharmacodynamics

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Variation in Extract Yield in Different Parts of Tinospora cordifolia


Affiliations
1 Department of Botany, Aligarh Muslim University, Aligarh-202002, India
2 Pharmacognosy and Ethnopharmacology Division, CSIR-National Botanical Research Institute, Lucknow-226001, India
     

   Subscribe/Renew Journal


Phytochemical screening is an important step which leads to the isolation of new and novel compounds. Solvent extract of the plant material with the help of different solvents such as n-hexane, chloroform, alcohol and aqueous revealed that in alcohol and aqueous solvent maximum extract yield obtained in all studied parts. Phytochemical screening analysis of the extracts revealed presence of tannins, phenolics, flavonoids, alkaloids, terpenes and steroids in most parts. In qualitative analysis, leaf showed presence of all tested phytochemicals followed by the stem and aerial ischolar_main of T. cordifolia.

Keywords

Extractive yield, Phytochemical, Qualitative analysis, Tinospora cordifolia.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Barnes J, Anderson LA and Phillipson JD. Herbal medicine. 3rd Edition, Pharmaceutical Press, London. 2007; 1-23.

  • Gurib-Fakim A. Medicinal plants: Tradition of yesterday and drugs of tomorrow. Review article. Mol. Aspects Med. 2006; 27 (1):1-93.

  • Sandhya B, Thomas S, Isabel W and Shenbagarathai R. Ethnomedicinal plants used by the valaiyan community of Piranmalai hills (Reserved forest), Tamil Nadu, India - A pilot study. Afr J Tradit Complement Altern Med. 2006; 3(1): 101-114.

  • Satyavati GV, Gupta AK and Tandon N. Medicinal plants of India, Indian Council of Medical Research, New Delhi, India. 1987.

  • Patwardhan B, Vaidhya ADB and Chorghade M. Ayurveda and Natural products drug discovery. Curr Sci. 2004; 86: 789-799.

  • Bhandari C.Vanaushadhi Chandroda (Chaukhamba Sanskrit Sansthan, Varanasi). 2006; 86.

  • Patwardhan B and Gautam M. Botanical immunodrugs: scope and opportunities, Drug Discov Today. 2005; 10: 495-502.

  • Patil M, Patki P, Kamath HV and Patwardhan B. Antistress activity of Tinospora cordifolia (wild) Miers., Indian Drugs. 1997; 34: 211-215.

  • Anonymous. Indian Pharmacopoeia, Guduchi (Published by Indian Pharmacopoeia Commission, Govt. Of India). 2007; 2037-2034.

  • Anonymous. The Ayurvedic Pharmacopoeia of India, (The Controller of Publications, Delhi). 1st Edn, 2001; 41-42.

  • Jain SK. Dictionary of Folk Medicine and Ethnobotany, (Deep Publishers, New Delhi).1991; 179-80.

  • Lalramnghinglova H. Ethno-Medicinal Plants of Mizoram, (Bishen Singh Mahendra Pal Singh, Dehradun). 2003; 283.

  • Singh V and Pandey RP. Ethnobotany of Rajasthan India, (Scientific publisher, Jodhpur, India). 1998; 203 - 231.

  • Sood SK, Parmar S and Lakhanpal TN. Ethnic plants of India used in cancer cure, (Bishen Singh Mahendra Pal Singh, Dehradun). 2005; 235.

  • Singh SS, Pandey SC, Srivastava S, Gupta VS, Patro B and Ghosh AC. Chemistry and medicinal properties of Tinospora cordifolia (Guduchi), Indian J Pharm. 2003; 35: 83 - 91.

  • Anonymous. The Ayurvedic Pharmacopoeia Of India (Department Of AYUSH, Ministry Of Health And Family Welfare, Government Of India, New Delhi). 2009; 70-72.

  • Chintalwar G, Jain A, Sipahimalani A, Banerji A, Sumariwalla P, Ramakrishnan R and Sainis K. An immunologically active arabinogalactan from Tinospora cordifolia, Phytochemistry. 1999; 52:1089 - 1093.

  • Bisset N and Nwaiwu J. Quaternary alkaloids of Tinospora species, Planta Med. 1983; 48: 275 - 279.

  • Choudhary N, Siddiqui MB, Azmat S and Khatoon S. Tinospora cordifolia: ethnobotany, phytopharmacology and phytochemistry aspects, IJPSR. 2013; 4: 891-899.

  • Harbone JB. Phytochemicals methods. London. Chapman and Hill. 1973.

  • Kokate CK, Purohit AP and Gokhale SB. Pharmacognosy. Nirali Prakashan. 2009; 6.16-6.17.

  • Evans WC and Trease GE. Trease and Evans pharmacognosy. W.B. Saunders, China. 2002; 193-407.

  • Khandelwal KR. Practical Pharmacognosy. Nirali Prakashan. 1995; 149-155.

  • Singh R, Singh SK and Arora S. Evaluation of antioxidant potential of ethyl acetate extract/fractions of Acacia auriculiformis A. Cunn. Fod Chem. Toxicol. 2007; 45: 1216-1223.

  • Han X, Shen T and Lou H. Dietry polyphenols and their biological significance. Int. J. Mol. Sci. 2007; 950-988.

  • Ali SS, Kasoju N, Luthra A, Singh A, Sharanabasava H, Sahuand A and Bora U. Indian medicinal herbs as source of antioxidants. Food Res. Int. 2008; 41: 1-15.

  • Pietta P. Flavonoids as Antioxidants. J. Nat. Prod. 2000; 63: 1035-1042.

  • Brahmachari G and Gorai D. Progress in the research on naturally occurring flavones and flavonols: An overview. Curr. Org. Chem. 2006; 10: 873-898.

  • Osuagwu GGE, Okwulehie IC and Emenike JO. Phytochemical and Mineral content of the leaves of four Nigerian Pterocarpus species. Int. J. Mol. Med. Adv. Sci. 2007; 3(1): 6 - 11.

  • Sodipo OA, Akiniyi JA and Ogunbamosu JU. Studies on certain characteristics of extracts of bark of Pansinystalia macruceras (K schemp) picrre Exbeille. Global J. Pure Appl. Sci.2000; 6: 83-87.

  • Raquel FE. Bacterial lipid composition and antimicrobial efficacy of cationic steroid compounds. Biochemica et Biophysica Acta. 2007; 2500-2509.

  • Okwu DE. Evaluation of chemical composition of medicinal plants belonging to Euphorbiaceae. Pak Vet. J. 2001; 14: 160-162.

  • Nobori T, Miurak k, Wud J, Takabayashik LA and Crson DA. Deletion of the cyclin-dependent kinase -4 inhibitor gene in multiple human cancers. Nature. 1994; 368(6473): 753-756.

  • Okwu DE and Okwu ME. Chemical composition of Spondias mombin linn. plant parts. J. Sustain. Agric. Environ. 2004; 6(2): 140-147.

  • Nyarko AA and Addy ME. Effects of aqueous extract of Adenia cissampeloides on blood pressure and serum analyte of hypertensive patients. Phytotherapy Res. 1990; 4(1): 25-28.


Abstract Views: 381

PDF Views: 2




  • Variation in Extract Yield in Different Parts of Tinospora cordifolia

Abstract Views: 381  |  PDF Views: 2

Authors

Namrta Choudhary
Department of Botany, Aligarh Muslim University, Aligarh-202002, India
M. B. Siddiqui
Department of Botany, Aligarh Muslim University, Aligarh-202002, India
Sayyada Khatoon
Pharmacognosy and Ethnopharmacology Division, CSIR-National Botanical Research Institute, Lucknow-226001, India
Shazia Bi
Pharmacognosy and Ethnopharmacology Division, CSIR-National Botanical Research Institute, Lucknow-226001, India

Abstract


Phytochemical screening is an important step which leads to the isolation of new and novel compounds. Solvent extract of the plant material with the help of different solvents such as n-hexane, chloroform, alcohol and aqueous revealed that in alcohol and aqueous solvent maximum extract yield obtained in all studied parts. Phytochemical screening analysis of the extracts revealed presence of tannins, phenolics, flavonoids, alkaloids, terpenes and steroids in most parts. In qualitative analysis, leaf showed presence of all tested phytochemicals followed by the stem and aerial ischolar_main of T. cordifolia.

Keywords


Extractive yield, Phytochemical, Qualitative analysis, Tinospora cordifolia.

References