Open Access
Subscription Access
Open Access
Subscription Access
Evaluation of Antitussive Activity of Alternanthera sessilis
Subscribe/Renew Journal
The aim of the present study was to look at the antitussive activity of the ethanol extract of Alternanthera sessilis whole plant (EAS) by Sulfur dioxide gas induce model in mice. Results were revealed that the MESI was found to produce significant antitussive activity when compared with control and codeine phosphate in a dose dependent manner. The EAS produced 51.1 and 29.2% inhibition of SO2 induced cough at doses of 250 and 500mg/kg respectively the standard antitussive drug codeine phosphate(10 and 20mg/kg.p.o) showed 45.2 and 25.3 % inhibition respectively.
Keywords
Alternanthera sessilis, Antitussive Activity, Sulfur Dioxide Gas Induce Model in Mice.
Subscription
Login to verify subscription
User
Font Size
Information
- Tripathi KD. Essentials of Medical Pharmacology. Jaypee Brothers, New Delhi, 1999; 4th edt: p.222.
- Goodman and Gillman's. The Pharmacological Basis of Therapeutics, McGraw-Hill, , 2005; 11th edt: p. 578.
- Sutovska M, Nosalova G, Franova S and Kardosova A. The antitussive activity of polysaccharides from Althaea officinalis, Arctium lappa and Prunus persica. Bratisl Lek Listy. 108 (2); 2007: 93-99.
- The Wealth of India. Raw materials, Vol 1(Revised), CSIR, New Delhi, 1985; 318-9. 5. Rastogi RP, Compendium of Indian medicinal plant, CDRI, Lucknow, 1993; 9th edt: p. 1970-9.
- Gupta AK. Indian medicinal plants, ICMR, New Delhi, 2004; 151-7.
- Sinha P, Arora VK, Wahi SP. Chemical investigation on Alternanthera sessilis. Indian Drug. 1; 1984: 139-40.
- Anandkumar BH, Sachidanand YN. Treatment of acne vulgaris with new polyherbal formulation clarina cream. Indian J Dermatol. 46; 2001: 1-3.
- Archana Borah, Yadav RNS and Unni BG. In vitro antioxidant and free radical scavenging activity of Alternanthera sessilis. IJPSR. 2 (6); 2011: 1502-1506
- Jalapue SS, Agarwal N, Patil MB, Chimkode R and Tripathi A. Antimicrobial and wound healing activities of leaves of Alternanthera sessilis. Int J Green Pharm. 2; 2008: 141-4.
- Srinivas Reddy C, Subhashini T and Krishnaveni B. Anti- Inflammatory Activity of Leaf Extracts of Alternanthera sessilis. Hygeia J D Med. 2(1); 2010: 54-57. Anand Sankar, Nikhila C, Lakshmiprasanna VC, Mobeena SK, Karunakar Kand Bharathi N. Evaluation of antitussive activity of Rosa centifolia. IJPSR. 2 (6); 2011: 1473-1475.
Abstract Views: 235
PDF Views: 2