Research Journal of Pharmacology and Pharmacodynamics

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Diuretic and Laxative Activity of Ethanolic Extract of Mollugo Pentaphylla Linn


Affiliations
1 School of Pharmaceutical Science & Research, Berhampur University, Berhampur, Odisha -760007, India
2 School of Pharmaceutical Sciences, SOA University, Bhubaneswar, Odisha-754030, India
     

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Crude ethanolic extract of Mollugo pentaphylla Linn. (family - Aizoaceae) was investigated for diuretic and laxative activity in albino rats at 200 and 400 mg/kg p.o. Which was compared with standard drugs Furosemide (10mg/kg, p.o.) and Agar agar (300mg/kg, p.o.) respectively. The extract was found to produce significant diuretic as well as laxative activity at dose 400 mg/kg. The plant was also found to possess the phytoconstituents like carbohydrates, alkaloids, gums, saponins, flavanoids, tanins and steroids.

Keywords

Mollugo Pentaphylla, Acute Toxicity Study, Diuretic Activity, Laxative Activity.
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  • Diuretic and Laxative Activity of Ethanolic Extract of Mollugo Pentaphylla Linn

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Authors

S. K. Sahu
School of Pharmaceutical Science & Research, Berhampur University, Berhampur, Odisha -760007, India
D. Das
School of Pharmaceutical Sciences, SOA University, Bhubaneswar, Odisha-754030, India
N. K. Tripathy
School of Pharmaceutical Science & Research, Berhampur University, Berhampur, Odisha -760007, India
H. K. Sundeep Kumar
School of Pharmaceutical Science & Research, Berhampur University, Berhampur, Odisha -760007, India

Abstract


Crude ethanolic extract of Mollugo pentaphylla Linn. (family - Aizoaceae) was investigated for diuretic and laxative activity in albino rats at 200 and 400 mg/kg p.o. Which was compared with standard drugs Furosemide (10mg/kg, p.o.) and Agar agar (300mg/kg, p.o.) respectively. The extract was found to produce significant diuretic as well as laxative activity at dose 400 mg/kg. The plant was also found to possess the phytoconstituents like carbohydrates, alkaloids, gums, saponins, flavanoids, tanins and steroids.

Keywords


Mollugo Pentaphylla, Acute Toxicity Study, Diuretic Activity, Laxative Activity.

References