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Biochemical Effects of Persea americana (Avocado) and Dacryodes edulis (African Pear) Extracts on Liver Function Test of Albino Wistar Rats


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1 Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, Nigeria
     

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The liver function tests of the animals fed P. americana showed that the enzyme activities of alanine aminotransferase (ALT) was 57.35±4.40IU/L, aspartate aminotransferase 77.44±3.53IU/L and alkaline phosphatase 170.73±6.52IU/L while the enzyme activity of those fed D. edulis was 45.57±2.28IU/L AST, 68.26±3.69IU/L AST and 153.36±19.08IU/L ALP. AST and ALT increased significantly (p<0.05) in the sera of rats administered P. americana pulp compared with those fed D. edulis. However, no significant difference was observed (p>0.05) was observed in the ALP activities of the three groups. The total cholesterol level of animals administered D. edulis (75.76±5.37mg/dl) was lower compared with those administered P. americana (115.75±22.6mg/dl).

Keywords

Coconut (Cosos nucifera), Calcium, Magnesium, Zinc.
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  • Biochemical Effects of Persea americana (Avocado) and Dacryodes edulis (African Pear) Extracts on Liver Function Test of Albino Wistar Rats

Abstract Views: 258  |  PDF Views: 0

Authors

Edokwe Chinelo
Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, Nigeria
Obidoa Onyechi
Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, Nigeria
Joshua Parker Elijah
Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, Nigeria

Abstract


The liver function tests of the animals fed P. americana showed that the enzyme activities of alanine aminotransferase (ALT) was 57.35±4.40IU/L, aspartate aminotransferase 77.44±3.53IU/L and alkaline phosphatase 170.73±6.52IU/L while the enzyme activity of those fed D. edulis was 45.57±2.28IU/L AST, 68.26±3.69IU/L AST and 153.36±19.08IU/L ALP. AST and ALT increased significantly (p<0.05) in the sera of rats administered P. americana pulp compared with those fed D. edulis. However, no significant difference was observed (p>0.05) was observed in the ALP activities of the three groups. The total cholesterol level of animals administered D. edulis (75.76±5.37mg/dl) was lower compared with those administered P. americana (115.75±22.6mg/dl).

Keywords


Coconut (Cosos nucifera), Calcium, Magnesium, Zinc.