Effect of Trichosanthes dioica (Fruits) Against Helminthes

The present communication deals with the laboratory studies carried out to ascertain the anthelmintic activity of methanolic extract of Trichosanthes dioica Roxb (fruits). Various concentrations (50 and 100 mg/ml) of extract were tested in the assay, which involved the determination of paralysis time and death time of the organisms. The methanol extract exhibited significant anthelmintic activity comparable to standard drug. The efficacy of methanolic extract of Trichosanthes dioica may be attributed to the phytochemicals present in the solvent extract. Further studies on isolation of active constituents are to be required.