Research Journal of Science and Technology

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Study of Anti Oxidant and Anti-Inflammatory Activity from Ethanol Fraction of Thuja occidentalis Linn


Affiliations
1 Dept. of Pharmacognosy, Sanjeevan College of Pharmacy, Dausa (Raj.), India
2 Dept. of Botany, University of Rajasthan, Jaipur (Raj.), India
     

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The present study was carried out to evaluate the antioxidant (in vitro) and anti-inflammatory (in vivo) activities of ethanol fraction of Thuja occidentalis Linn. (Cupressaceae). 1, 1-Diphenyl-2-picryl-hydrazyl (DPPH) radical, superoxide anion radical, hydroxyl radical scavenging, nitric oxide scavenging and lipid peroxidation were carried out to evaluate the antioxidant potential of the extract. Anti-inflammatory activity was performed by carrageenan induced paw oedema and cotton pellet granuloma models. Both the in vitro and in vivo were found significant.

Keywords

Thuja occidentalis, Anti-Inflammatory, Antioxidant Activity.
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  • Study of Anti Oxidant and Anti-Inflammatory Activity from Ethanol Fraction of Thuja occidentalis Linn

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Authors

S. K. Dubey
Dept. of Pharmacognosy, Sanjeevan College of Pharmacy, Dausa (Raj.), India
A. Batra
Dept. of Botany, University of Rajasthan, Jaipur (Raj.), India

Abstract


The present study was carried out to evaluate the antioxidant (in vitro) and anti-inflammatory (in vivo) activities of ethanol fraction of Thuja occidentalis Linn. (Cupressaceae). 1, 1-Diphenyl-2-picryl-hydrazyl (DPPH) radical, superoxide anion radical, hydroxyl radical scavenging, nitric oxide scavenging and lipid peroxidation were carried out to evaluate the antioxidant potential of the extract. Anti-inflammatory activity was performed by carrageenan induced paw oedema and cotton pellet granuloma models. Both the in vitro and in vivo were found significant.

Keywords


Thuja occidentalis, Anti-Inflammatory, Antioxidant Activity.