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New System for Identification of Propranolol Tablet (Inderal)


Affiliations
1 Additional Director andDirector (i/c)-Retired, Forensic Sciences Department, Mylapore, Chennai, India
2 School of Basic Medical Sciences, Faculty of Medicine, Universiti Sultan Zainal Abidin (UniSZA), Kuala Terengganu, Malaysia
3 Former Student of Women's Christian College, Chennai, India
4 People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India
     

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Various new drugs are being introduced in the market. This proves a hectic problem for Toxicologist to identify the exact nature of the drug and its metabolites in the viscera for cases involving death due to drug poisoning. When a case is taken for drug analysis, we have to be more exhaustive in ruling out drugs. For identification of Inderal tablets, a new Thin Layer chromatography system has been developed. After systematic trials, the paper has found out a new solvent system with spray for eluting Inderal tablets.

Keywords

Propranolol – TLC.
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  • Essentials of Forensic Medicine & Toxicology -By K.S. Narayan Reddy & O.P. Murthy.

  • Parikh's Textbook of Medical Jurisprudence & Toxicology- By C.K. Parikh.

  • Textbook of Medical Jurisprudence & Toxicology - By Jaising Modi.

  • Textbook of Bio-Chemistry - By West & Todd.

  • Casarett and Doull's Toxicology-The Basic Science of Poisons: By Curtis. D. Klaassen.

  • Principles of Forensic Medicine & Toxicology - By Rajesh Bardale.

  • Egon Stahl-Thin Layer Chromatography - 2nd edition 1990.

  • Isolation and Identification of Drugs in Pharmaceuticals, body fluids and post-mortem material – By E.C.G. Clarke. - 2nd edition.


Abstract Views: 138

PDF Views: 0




  • New System for Identification of Propranolol Tablet (Inderal)

Abstract Views: 138  |  PDF Views: 0

Authors

Kamalakshi Krishnamurthy
Additional Director andDirector (i/c)-Retired, Forensic Sciences Department, Mylapore, Chennai, India
Thant Zin
School of Basic Medical Sciences, Faculty of Medicine, Universiti Sultan Zainal Abidin (UniSZA), Kuala Terengganu, Malaysia
K. Priyamvatha
Former Student of Women's Christian College, Chennai, India
Mahadeva Rao U. S.
School of Basic Medical Sciences, Faculty of Medicine, Universiti Sultan Zainal Abidin (UniSZA), Kuala Terengganu, Malaysia
M. Suganya
People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India

Abstract


Various new drugs are being introduced in the market. This proves a hectic problem for Toxicologist to identify the exact nature of the drug and its metabolites in the viscera for cases involving death due to drug poisoning. When a case is taken for drug analysis, we have to be more exhaustive in ruling out drugs. For identification of Inderal tablets, a new Thin Layer chromatography system has been developed. After systematic trials, the paper has found out a new solvent system with spray for eluting Inderal tablets.

Keywords


Propranolol – TLC.

References