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A Review on Phytochemical Investigation of Gymnema sylvestre Leaves


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1 Pravara Rural College of Pharmacy Pravaranagar, Loni, Dist.- Ahmednagar, Maharashtra, India
     

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Gymnema sylvestre is a plant included in Apocynaceae family and is located in many regions of Asia, Africa and Australia. It is known to have blood glucose lowering potential and, thus, is widely used in traditional and Ayurvedic systems of medicine. A scrutiny of literature revealed some notable pharmacological activities of the plant such as antidiabetic, antiobesity, hypolipidaemic, antimicrobial, free radical scavenging and anti-inflammatory. The phytoconstituents responsible for sweet suppression activity includes triterpene saponins known as gymnemic acids, gymnemasaponins, and a polypeptide, gurmarin. Efforts have been made to prepare gudmar dried extract. These extracts were subjected for preliminary qualitative analysis, quantitative estimation of terpenoides, alkaloids and various other compounds. The present review is an attempt to highlight the phytochemical screening as well as its extraction process. Also chromatographic studies gave the presence of different compounds which can be used in creating monograph for this species.

Keywords

Gymnema sylvestre, phytochemistry, gymnemic acid, qualitative and quantitative analysis, extraction.
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  • A Review on Phytochemical Investigation of Gymnema sylvestre Leaves

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Authors

Sejal M. Karwa
Pravara Rural College of Pharmacy Pravaranagar, Loni, Dist.- Ahmednagar, Maharashtra, India
Dattaprasad N. Vikhe
Pravara Rural College of Pharmacy Pravaranagar, Loni, Dist.- Ahmednagar, Maharashtra, India
Ravindra S. Jadhav
Pravara Rural College of Pharmacy Pravaranagar, Loni, Dist.- Ahmednagar, Maharashtra, India

Abstract


Gymnema sylvestre is a plant included in Apocynaceae family and is located in many regions of Asia, Africa and Australia. It is known to have blood glucose lowering potential and, thus, is widely used in traditional and Ayurvedic systems of medicine. A scrutiny of literature revealed some notable pharmacological activities of the plant such as antidiabetic, antiobesity, hypolipidaemic, antimicrobial, free radical scavenging and anti-inflammatory. The phytoconstituents responsible for sweet suppression activity includes triterpene saponins known as gymnemic acids, gymnemasaponins, and a polypeptide, gurmarin. Efforts have been made to prepare gudmar dried extract. These extracts were subjected for preliminary qualitative analysis, quantitative estimation of terpenoides, alkaloids and various other compounds. The present review is an attempt to highlight the phytochemical screening as well as its extraction process. Also chromatographic studies gave the presence of different compounds which can be used in creating monograph for this species.

Keywords


Gymnema sylvestre, phytochemistry, gymnemic acid, qualitative and quantitative analysis, extraction.

References