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Design and Development of Aloe vera Lotions and Determination of their Sun Protection Factor


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1 Bapatla College of Pharmacy, Bapatla-522101, India
     

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Sun light causes damage to skin by inducing photoaging, photocarcinogenisis. Aloe vera is most popular in the treatment of dermatological disorders. In this study, in to the calamine lotion aloe gel (conventional lotion), a novel lotion containing freeze dried aloe powder beads and freeze dried aloe powder lotion were incorporated. The aim of this study is to compare the efficacy of novel lotion (freeze dried aloe powder beads and freeze dried aloe powder lotion) and conventional lotion (aloe gel). Aloe gel beads were prepared by using the ionic gelation technique. Beads were in spherical shape with a diameter of 0.510±0.143 mm. The novel, conventional lotion were evaluated for the colour, PH of preparation, sedimentation volume, redispersibility, spreadability, rheological, In vitro and In vivo sun protection factor(SPF). For conventional lotion SPF was found to be 6.39±0.1 where as for novel lotion containing freeze dried aloe powder beads SPF was found to be 13.52±0.21. It was found that novel lotion containing freeze dried aloe powder beads provides greater sunscreen protection than the conventional lotion. In vivo SPF values for novel lotion are higher than the conventional lotion.
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  • Design and Development of Aloe vera Lotions and Determination of their Sun Protection Factor

Abstract Views: 275  |  PDF Views: 0

Authors

V. Sai Kishore
Bapatla College of Pharmacy, Bapatla-522101, India
N. Balaji
Bapatla College of Pharmacy, Bapatla-522101, India
K. Srikanth
Bapatla College of Pharmacy, Bapatla-522101, India
J. Hemanth
Bapatla College of Pharmacy, Bapatla-522101, India

Abstract


Sun light causes damage to skin by inducing photoaging, photocarcinogenisis. Aloe vera is most popular in the treatment of dermatological disorders. In this study, in to the calamine lotion aloe gel (conventional lotion), a novel lotion containing freeze dried aloe powder beads and freeze dried aloe powder lotion were incorporated. The aim of this study is to compare the efficacy of novel lotion (freeze dried aloe powder beads and freeze dried aloe powder lotion) and conventional lotion (aloe gel). Aloe gel beads were prepared by using the ionic gelation technique. Beads were in spherical shape with a diameter of 0.510±0.143 mm. The novel, conventional lotion were evaluated for the colour, PH of preparation, sedimentation volume, redispersibility, spreadability, rheological, In vitro and In vivo sun protection factor(SPF). For conventional lotion SPF was found to be 6.39±0.1 where as for novel lotion containing freeze dried aloe powder beads SPF was found to be 13.52±0.21. It was found that novel lotion containing freeze dried aloe powder beads provides greater sunscreen protection than the conventional lotion. In vivo SPF values for novel lotion are higher than the conventional lotion.