![Open Access](https://i-scholar.in/lib/pkp/templates/images/icons/fulltextgreen.png)
![Restricted Access](https://i-scholar.in/lib/pkp/templates/images/icons/fulltextred.png)
B-Lymphocytes Level in Peripheral Blood among Patients with Metabolic Syndrome and Diabetes Mellitus Type 2
A considerable suggestion exists between the leukocyte count, lymphocyte (lymph) dysfunction and the possibility of developing DMt2. Aim of the study was to investigate the CD19 +expression of B- lymph in peripheral blood in patients with metabolic syndrome (MS) without and with Diabetes mellitus type 2 (DMt2). A prospective, one-year, comparative, observational study was performed. In 26 MS patients without DMt2 (n1=26) and 69 with DMt2 (n2=69) were measured and compared the levels of leucocytes and CD19+ B- lymph subtypes in peripheral blood by flow-cytometric analysis. The leucocytes count is in normal range in both groups with MS. DMt2 patients have a higher leucocytes count (n1=6.93±1.92.109 vs n2=7.27±1.85.109; р= 0,04) in the referent range. The percentage of the common lymphocytes population was also higher among n1 patients compared to n2, but without significant difference in their absolute count [(n1=38,26%±7,43% vs. n2=33,42%±7,08%) and (n1=2.58±0.8.109 vs. n1=3,45±0,67.109)]. The percentage ratio and absolute count of СD19+ B- lymphocytes subtypes in patients from both groups was lower than referent values, but without significant difference between the two groups.The levels of СD19+B-lymphocytes in peripheral blood are lower in patients with MS irrespective of the level of glycaemia.
Keywords
Metabolic Syndrome, B-Lymphocytes, Type 2 Diabetes Mellitus Risk, Flow-Cytometry.
User
Font Size
Information
![](https://i-scholar.in/public/site/images/abstractview.png)
Abstract Views: 258
![](https://i-scholar.in/public/site/images/pdfview.png)
PDF Views: 163