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Pulmonary Nocardiosis Mimicking Tuberculosis-A Case Report


Affiliations
1 Department of Microbiology, Saraswathi Institute of Medical Sciences, Anwarpur, Hapur Uttar Pradesh, India
     

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A 68 year old male from farming background presented with productive cough, dyspnea with purulent sputum who acquired pulmonary Nocardiosis. Sputum smear microscopy and culture revealed the presence of Nocardia species. The patient was treated with Cotrimoxazole and Amikacin.

Keywords

Pulmonary Disease, Nocardia.
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  • Feigin DS. Nocardiosis of the lung: chest radiographic findings in 21 cases. Radiology. 1986;159(1):9-14.
  • Menéndez R, Cordero PJ, Santos M, Gobernado M, Marco V. Pulmonary infection with Nocardia species: a report of 10 cases and review. Eur Respir J. 1997;10(7):1542-6.
  • Silva AC, Martins EM, Marchiori E, Neto GT. Nocardiose pulmonar em paciente com síndrome da imunodeficiência adquirida: relato de caso. Radiol Bras. 2002;35(4):235-8.
  • Pifarré R, Teixidó B, Vilá M, Duran M, García JM, Morera J. Pulmonary nocardiosis as a cause of radiographic imaging of multiple pulmonary nodules [Article in Spanish]. Arch Bronconeumol. 2001;37(11):511-2.
  • Kramer MR, Uttamchandani RB. The radiographic appearance of pulmonary nocardiosis associated with AIDS. Chest. 1990;98(2):382-5.
  • Baldi BG, Santana AN, Takagaki TY. Pulmonary and cutaneous nocardiosis in a patient treated with corticosteroids. J Bras Pneumol. 2006;32(6):592-5.
  • Matulionyte R, Rohner P, Uçkay I, Lew D, Garbino J. Secular trends of nocardia infection over 15 years in a tertiary care hospital. J Clin Pathol. 2004;57(8):807-12.
  • Ferrer A, Llorenç V, Codina G, de Gracia-Roldán J. Nocardiosis and bronchiectasis. An uncommon association? [Article in Spanish] Enferm Infecc Microbiol Clin. 2005;23(2):62-6.
  • Díez-García MJ, Andreu AL, Chiner E. Bronchopneumonia due to Nocardia asteroides in a man with chronic obstructive pulmonary disease Arch Bronconeumol. 2005;41(11):642-3.
  • Filice GA. Inhibition of Nocardia asteroides by neutrophils.J Infect Dis 1985; 151: 47–56.
  • Deem RL, Doughty FA, Beaman BL. Immunologically specific direct T-lymphocytemediated killing of Nocardia asteroides. J Immunol 1983; 130: 2401–2406.
  • Black CM, Beaman BL, Donnovan RM, Goldstein E. Effect of virulent and less virulent strains of Nocardia asteroides on acid-phosphatase activity in alveolar and peritoneal macrophages maintained in vitr0. J Infect Dis, 1983; 148: 117– 124.
  • Fauci, Braunwald, Kasper, Hauser, Longo, Jameson, Loscalzo. Harrison’s principles of Internal Medicine. 17th edition, volume 1, part 7: infectious diseases, section 7, pp 992-996.
  • Randhawa HS et al. Prevalence of nocardiosis in bronchopulmonary disease. Indian J Med Res 1973; 61:689
  • Singh M., Kalian BM, Sandhu RS, et al. Occurrence of pulmonary nocardiosis in Amritsar. Indian J Chest Dis Allied Sci 1982; 24:6 16. Gupta Ketal. Pulmonary Nocardiosis. Indian J Chest Dis Allied Sci 1996; 38:197
  • Gupta D, Mishra R, Agarwal PS et al. Hospital acquired pulmonary nocardiosis complicating polymyositis. JAPI 1995; 43(9) 641 18. Gaude GS et al. Clinical profile ofpulmonary Nocardiosis. Indian J Chest Dis Allied Sci 1994; 41:155
  • Lerner PI. Nocardia species. In: Mandell GL, Douglas RG, Bennett JE, eds. Principles and Practice of Infectious Diseases. 2nd Edn. New York, John Wiley & Sons, 1985; pp. 192–206.
  • Kirch JA, Stinson EB, Remington JS. Nocardia infection in heart transplantation patients. Ann Intern Med 1975; 82: 18–26.
  • Goltz HA, Lavery DP, Kapila R. Actinomycetales infection in the acquired immunodeficiency syndrome. Ann Intern Med 1985; 102: 203–205.
  • Anil Kumar, Asmita Mehta, Ghanshyam Kavathia, Molly Madan. Pulmonary and extrapulmonary Tuberculosis along with pulmonary Nocardiosis in a patient with Human Immunodeficiency virus infection: Journal of Clinical and Diagnostic Research. 2011 Feb, Vol- 5(1):109-111
  • Miguel Abidon Aidê; Silvia Soares Lourenço; Edson Marchiori; Gláucia ZanettiIV; Pedro Juan José MondinoV Pulmonary nocardiosis in a patient with chronic obstructive pulmonary disease and bronchiectasis* Jornal Brasileiro de Pneumologia J. bras. pneumol. vol.34 no.11 São Paulo Nov. 2008
  • Vishal Chopra, G C Ahir, Gian Chand and P. K. Jain. Pulmonary nocardiosis mimicking pulmonary tuberculosis. The Indian Journal of Tuberculosis: 2001 ,48 , 211
  • R. Menéndez, P.J. Cordero, M. Santos, M. Gobernado, V. Marco Pulmonary infection with Nocardia species: a report of 10 cases and review Eur Respir J 1997; 10: 1542–1546
  • Kramer MR, Uttamchandani RB. The radiographic appearance of pulmonary nocardiosis associated with AIDS. Chest 1990; 98: 382–385.
  • R Amatya, R Koirala, B Khanal, SS Dhakal; Nocardia brasiliensis primary pulmonary nocardiosis with subcutaneous involvement in an immunocompetent patient. Indian Journal of Medical Microbiology : 2011, Volume : 29, Issue : 1, Page : 68-70
  • Presant CA, Wiernik PH, Serpick AA. Factors affecting survival in nocardiosis. Am Rev Respir Dis 1973; 108: 1444–1448.
  • Saubolle MA. In vitro susceptibility testing of clinical isolates of Nocardia. Clin Microbiol Newsl 1993; 15:169–172.
  • Runyon EH. Nocardia asteroides: studies of its pathogenicity and drug sensitivities. J Lab Clin Med 1951;37: 713–725.
  • Farina C, Boiron P, Goglio A, Provost F. Human Nocardiosis in northern Italy from 1982 to 1992: Northern Italy Collaborative Group on Nocardiosis. Scan J Infect Dis 1995; 27: 23–27.
  • Gombert ME, Aulicino TM. Synergism of imipenem and amikacin in combination with other antibiotics against Nocardia asteroides. Antimicrob Agents Chemother 1983; 24: 810–811.
  • Gombert ME, Aulicino TM, du Bouchet L, Silverman GE, Sheinbaum WM. Therapy of experimental cerebral nocardiosis with imipenem, amikacin, trimethoprimsulfamethoxazole, and minocycline. Antimicrob Agents Chemother 1986; 30: 270–273. 34. Curry WA. Human nocardiosis: a clinical review with selected case reports. Arch Intern Med 1980; 140: 818–826.
  • Byrne E, Brophy BP, Perrett LV. Nocardia cerebral abscesses: new concepts in diagnosis, management andprognosis. J Neurol Neurosurg Psychiatry 1979; 42: 1038–1045.
  • Fernandez-Guerrero ML, Torres A, Díaz Curiel M, Soriano F. Successful treatment of nocardial thigh abscess and possible brain abscess with co-trimoxazole. Eur J Clin Microbiol 1985; 4: 430–431.
  • Nisbet, Mitzi MBChB; Eaton, Tam FRACP; Roberts, Sally FRACP; Milne, David FRANZCR; Rogers, Karen BSc; Woodhouse, Andrew FRACP; Pulmonary Nocardiosis in an Immunocompetent Host: Successful Treatment With Moxifloxacin and Minocycline of Multiple Drug-Resistant Nocardia transvalensis Complex;Infectious Diseases in Clinical Practice: January 2006 - Volume 14 - Issue 1 - pp 55-58
  • Brown-Elliot B, Ward C, Crist L, et al. In vitro activities of linezolid against multiple Nocardia species. Antimicrob Agents Chemother. 2001;45:1295-1297.
  • Moylett E, Pacheco B, Brown-Elliot T, et al. Clinical experience with linezolid for the treatment of Nocardia infection. Clin Infect Dis. 2003;36:313-318.
  • Khadori N, Shawar R, Gupta R, et al. In vitro antimicrobial susceptibilities of Nocardia species. Antimicrob Agents Chemother. 1993;37:882-884.
  • Yazaw K, Mikami Y. In vitro antimicrobial activity of the new fluoroquinolone, grepafloxacin, against pathogenic Nocardia spp. J Antimicrob Chemother. 1995;35:541-544.

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  • Pulmonary Nocardiosis Mimicking Tuberculosis-A Case Report

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Authors

Deepak Gupta
Department of Microbiology, Saraswathi Institute of Medical Sciences, Anwarpur, Hapur Uttar Pradesh, India
Gunjan Dutta
Department of Microbiology, Saraswathi Institute of Medical Sciences, Anwarpur, Hapur Uttar Pradesh, India

Abstract


A 68 year old male from farming background presented with productive cough, dyspnea with purulent sputum who acquired pulmonary Nocardiosis. Sputum smear microscopy and culture revealed the presence of Nocardia species. The patient was treated with Cotrimoxazole and Amikacin.

Keywords


Pulmonary Disease, Nocardia.

References