International Journal of Contemporary Medicine

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Current Clinical Profile of Ocular HIV Disease in India


Affiliations
1 Department of Pathology, Department of E.N.T., Santosh Medical College and Hospital, Ghaziabad, India
2 Department of Ophthalmology, Department of E.N.T., Santosh Medical College and Hospital, Ghaziabad, India
3 Department of E.N.T., Santosh Medical College and Hospital, Ghaziabad, India
4 Department of Microbiology, Narayan Medical College and Hospital, Sasaram, India
5 Rotary Eye Hospital Maranda, Palampur, HP, India
     

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Purpose: To describe current ophthalmic and systemic findings in 116 patients with Human Immunodeficiency Virus (HIV) infection examined at three referral eye centers in India and to establish safety guidelines for health care personnel's. Method: A complete ophthalmological examination was performed on each patient. Relevant investigations were carried out on selected patients. Results: The most common lesion was cytomegalovirus (CMV) retinitis. Other lesions in decreasing order of frequency are cotton-wool spots, chorioretinitis, endogenous endophthalmitis, anterior uveitis, and molluscum contagiousm. The most common systemic infection was pulmonary tuberculosis (50%). The others were oral candidiasis (41.4%), Pneumocystis carinii pneumonia (11.4%), HIV enteropathy (12.8%) and toxoplasmosis (4.2%). Conclusion: The most common ocular lesion among HIV patients in India is CMV retinitis. With wider availability of cost-effective HAART, clinical and epidemiological profile of HIV in India has undergone transition. Guidelines for aseptic measures in HIV infected patients have been clearly defined now. Physicians and Ophthalmologists should work in tandem to manage ocular disease and opportunistic infections.

Keywords

Human Iimmunodeficiency Virus (HIV), Acquired Immune Deficiency Syndrome (AIDS), Highly Active aAntiretroviral Therapy (HAART), Cytomegalovirus (CMV).
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  • Current Clinical Profile of Ocular HIV Disease in India

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Authors

Prachi Kumar
Department of Pathology, Department of E.N.T., Santosh Medical College and Hospital, Ghaziabad, India
Rahul Bhargava
Department of Ophthalmology, Department of E.N.T., Santosh Medical College and Hospital, Ghaziabad, India
Shreya Sardana
Department of E.N.T., Santosh Medical College and Hospital, Ghaziabad, India
Abhay Sood
Department of E.N.T., Santosh Medical College and Hospital, Ghaziabad, India
Manjushri Kumar
Department of Microbiology, Narayan Medical College and Hospital, Sasaram, India
SK Sharma
Rotary Eye Hospital Maranda, Palampur, HP, India

Abstract


Purpose: To describe current ophthalmic and systemic findings in 116 patients with Human Immunodeficiency Virus (HIV) infection examined at three referral eye centers in India and to establish safety guidelines for health care personnel's. Method: A complete ophthalmological examination was performed on each patient. Relevant investigations were carried out on selected patients. Results: The most common lesion was cytomegalovirus (CMV) retinitis. Other lesions in decreasing order of frequency are cotton-wool spots, chorioretinitis, endogenous endophthalmitis, anterior uveitis, and molluscum contagiousm. The most common systemic infection was pulmonary tuberculosis (50%). The others were oral candidiasis (41.4%), Pneumocystis carinii pneumonia (11.4%), HIV enteropathy (12.8%) and toxoplasmosis (4.2%). Conclusion: The most common ocular lesion among HIV patients in India is CMV retinitis. With wider availability of cost-effective HAART, clinical and epidemiological profile of HIV in India has undergone transition. Guidelines for aseptic measures in HIV infected patients have been clearly defined now. Physicians and Ophthalmologists should work in tandem to manage ocular disease and opportunistic infections.

Keywords


Human Iimmunodeficiency Virus (HIV), Acquired Immune Deficiency Syndrome (AIDS), Highly Active aAntiretroviral Therapy (HAART), Cytomegalovirus (CMV).

References