Indian Journal of Drugs and Diseases

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Objectives: Hematological and biochemical analysis studies of ruminant vertebrates (cow, sheep and goat) will provide us an acceptable method for understanding the ecological relationship among the vertebrates. Methods: Haematological/Biochemical studies were carried out on blood from the ruminants: Goat (Capra hircus-L), sheep (Ovis Aries dolrchra), cattle (Bos taurus) and human (Homosapiens) as control. Results: Electrophoretically, goat blood revealed three different Hb polymorphic types: HbAA (45%), HbAS (50%) and HbSS (5%). Only the 'O' Rh blood group was observed in all cases, and GST values of 4.05-6.30 I.U were obtained on the other hand. Cow Hb electrophoresis produced two patterns corresponding to the human HbAA and HbAS types. Only the 'O' Rh- blood group was obtained in all cases and GST values of 2.85-5.02 I.U were obtained, while sheep blood produced only the HbAA-type, only the 'O' blood group was identified in all case. GST activity values were in the range of 3.05-4.52 IU. Conclusion: These results could point to a definite haematological and biochemical similarity between man and ruminants and thus serves as a springboard for further genetic studies using lower vertebrate's as research models.

Keywords

Haemoglobin, Glutathione-S-transferase, Genotype, Erythrocyte
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