Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Hyperlipidemia that Induced in Male Rats and Role of Flavonoids Extract of Quercus infectoria in Treatment


Affiliations
1 Medical Laboratory Department, University of Al-Qalam College, Iraq
     

   Subscribe/Renew Journal


The aim of the study demonstrates flavonoids of Quercus infectoria as anti-hyperlipidemia. 20 adult male rats used and divided to four equal groups (each group consist 5 rats); rats received ad libidium, rats were given normal water containing 0.5% of hydrogen peroxide and 1% of cholesterol in the feed for 60 days for induction of hyperlipidemia. Hyperlipidemia rats treated with (50mg/kg/daily) flavonoids, fourth Hyperlipidemia rats treated with (100mg/kg/daily) flavonoids. The results show non-significant changes (P < 0.05) in levels of HMG-raductase compare with control group. in hyperlipidemia rats, levels of malonedialdehyied (MDA) show significant increase (P < 0.05) in and significant decrease (P < 0.05) in levels of glutathione (GSH) and catalase compare with control group. While, after using flavonoids extract in treatment, the results showed non-significant changes (P < 0.05) in HMG-raductase, MDA, GSH and catalase compare with control group. It was concluded that flavonoids extract of Q. infectoria extract has been a protective effect in rats with hyperlipidemia.

Keywords

Quercus infectoria, Hyperlipidemia, HMG-Raductase.
Subscription Login to verify subscription
User
Notifications
Font Size


Abstract Views: 457

PDF Views: 0




  • Hyperlipidemia that Induced in Male Rats and Role of Flavonoids Extract of Quercus infectoria in Treatment

Abstract Views: 457  |  PDF Views: 0

Authors

Marwa Amer Shakir
Medical Laboratory Department, University of Al-Qalam College, Iraq
Iman Nozad Mahmood
Medical Laboratory Department, University of Al-Qalam College, Iraq

Abstract


The aim of the study demonstrates flavonoids of Quercus infectoria as anti-hyperlipidemia. 20 adult male rats used and divided to four equal groups (each group consist 5 rats); rats received ad libidium, rats were given normal water containing 0.5% of hydrogen peroxide and 1% of cholesterol in the feed for 60 days for induction of hyperlipidemia. Hyperlipidemia rats treated with (50mg/kg/daily) flavonoids, fourth Hyperlipidemia rats treated with (100mg/kg/daily) flavonoids. The results show non-significant changes (P < 0.05) in levels of HMG-raductase compare with control group. in hyperlipidemia rats, levels of malonedialdehyied (MDA) show significant increase (P < 0.05) in and significant decrease (P < 0.05) in levels of glutathione (GSH) and catalase compare with control group. While, after using flavonoids extract in treatment, the results showed non-significant changes (P < 0.05) in HMG-raductase, MDA, GSH and catalase compare with control group. It was concluded that flavonoids extract of Q. infectoria extract has been a protective effect in rats with hyperlipidemia.

Keywords


Quercus infectoria, Hyperlipidemia, HMG-Raductase.



DOI: https://doi.org/10.37506/v14%2Fi1%2F2020%2Fijfmt%2F192950