Indian Journal of Forensic Medicine & Toxicology

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Biochemical Toxicity of Organophosphate Pesticide Metasystox in Fish Channa Punctatus


Affiliations
1 Department of Biochemistry, B.S.D.B.A. Government Medical College, Kannauj, India
2 Department of Biotechnology, BabaSaheb Bhimrao Ambedkar Central University, Lucknow, India
3 Department of Biochemistry, M.G.M. Medical College, Navi Mumbai, India
     

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Objective: To study the biochemical parameters of serum cholesterol and serum glutamate pyruvate transaminase in fish channa punctatus, exposed under pesticide metasystox.

Materials and Methods: This study was concluded in fish channa punctatus, exposed 24 to 96 hours, to four different concentration of metasystox pesticide. Serum cholesterol and S.G.P.T. levels were estimated as biochemical biomarkers.

Result: There were significantly increase in serum cholesterol (Hypercholesterolemia) and S.G.P.T observed in metasystox pesticide exposed on fish channa punctatus, about at all concentration and time intervals.

Conclusion: The hypercholesterolemia and elevated aminotransferase (S.G.P.T) due to metasystox toxicity referred as biomarkers for the disorder like myocardial infarction, heart attack, hepatitis biliary obstruction, alcoholic cirrhosis, cancer, toxic hepatitis etc, in human beings


Keywords

OPP (Organophosphate Pesticide), SGPT (Serum Glutamate pyruvate Transaminase), Metasystox
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  • Biochemical Toxicity of Organophosphate Pesticide Metasystox in Fish Channa Punctatus

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Authors

B. P. Mishra
Department of Biochemistry, B.S.D.B.A. Government Medical College, Kannauj, India
M. Y. Khan
Department of Biotechnology, BabaSaheb Bhimrao Ambedkar Central University, Lucknow, India
Z. G. Badade
Department of Biochemistry, M.G.M. Medical College, Navi Mumbai, India
M. Chandravathi
Department of Biochemistry, M.G.M. Medical College, Navi Mumbai, India
Deepak
Department of Biochemistry, B.S.D.B.A. Government Medical College, Kannauj, India

Abstract


Objective: To study the biochemical parameters of serum cholesterol and serum glutamate pyruvate transaminase in fish channa punctatus, exposed under pesticide metasystox.

Materials and Methods: This study was concluded in fish channa punctatus, exposed 24 to 96 hours, to four different concentration of metasystox pesticide. Serum cholesterol and S.G.P.T. levels were estimated as biochemical biomarkers.

Result: There were significantly increase in serum cholesterol (Hypercholesterolemia) and S.G.P.T observed in metasystox pesticide exposed on fish channa punctatus, about at all concentration and time intervals.

Conclusion: The hypercholesterolemia and elevated aminotransferase (S.G.P.T) due to metasystox toxicity referred as biomarkers for the disorder like myocardial infarction, heart attack, hepatitis biliary obstruction, alcoholic cirrhosis, cancer, toxic hepatitis etc, in human beings


Keywords


OPP (Organophosphate Pesticide), SGPT (Serum Glutamate pyruvate Transaminase), Metasystox

References