Indian Journal of Forensic Medicine & Toxicology

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Estimation of Post Mortem Interval by Means of Changes in the Eye-vitreous Humour Potassium Levels


Affiliations
1 Seth G.S. Medical College , KEM Hospital, Mumbai, India
2 Nmdvps's Dr. V.N. Pawar Maratha Vidya Prasarak Samaj's Dr. Vasantrao Pawar Medical College Hospital and Research Centre, Nashik, India
     

   Subscribe/Renew Journal


The present study was carried out in Shri. Vasantrao Naik Government Medical College, Yavatmal. The dead bodies brought to the mortuary were used as material for collection of vitreous humour sample from the eyes of deceased. The vitreous analytes have been investigated to establish their correlationship with PMI or time since death. A significant linear correlationship, at various degrees, was seen to exist between PMI and vitreous potassium

Keywords

Potassium, Vitreous Humour, Post Mortem Interval
Subscription Login to verify subscription
User
Notifications
Font Size


  • Coe JI. Postmortem chemistries on human vitreous humor. Am J Clin Pathol 1969;51:741-50

  • Coe JI. Some further thoughts and observations on postmortem chemistries. The Forensic Science Gazette1973;5:2-6

  • Coe JI, Apple FS. Variations in vitreous humor chemical values as a result of instrumentation. J ForensicSci1985;30:828-35.

  • Coe JI. Vitreous potassium as a measure of the postmortem interval: an historical review and critical evaluation. Forensic Sci Int 1989;42:201- 13.

  • Stephens RJ, Richards RG.Vitreous humor chemistry: the use of potassium concentration for the prediction of the postmortem interval. J Forensic Sci 1987;32:503-9.

  • Madea B and Henssge C. Eye changes after death. IN: Henssge C and Knight B. The Estimation of the Time since Death in the Early Postmortem Period. London: Arnold Publishers; 1995. p. 106- 137.

  • James RA, Hoadley PA and Sampson BG. Determination of postmortem interval by sampling vitreous humor. American J Forensic Medicine Pathology 1997 Jun; 18(2):158-162.

  • Sturner WQ. The vitreous humour: postmortem potassium changes. Lancet 1963;1:807-8

  • Munoz JI, Suarez – Penaranda JM, oteroXL Rodriguez calvo MS, costas E, Miguen concheiro. A new perspective on the estimation of postmortem interval (PMI) based on vitreous. Forensic Sci Int 2002,125 (1) : 67 – 74

  • G. Adjutantis, A. Coutselinis, Estimation of the time of death by potassium levels in the vitreous humour, Forensic Sci. Int. 1 (1972) 55-60.

  • Swift PG, Worthy E, Emery JL. Biochemical state of the vitreous humour of infants at necropsy. Arch Dis Child 1974;49:680-5.

  • Tagliaro F, Bortolotti F, Manetto G, Cittadini F, Pascali VL, Marigo M. Potassium concentration differences in the vitreous humour from the two eyes revisited by microanalysis with capillary electrophoresis. J Chromatogr A 2001;924:493-8.

  • Tedeschi Forensic Medicine: a study of trauma and environmental hazards, Vol. II Postmortem chemistry of blood, cerebrospinal fluid and vitreous humour, 1033-1060.

  • Wheeler MS, Butts JD, Hudson P. Vitreous humor magnesium in alcoholics. Am J Forensic Med Pathol 1983;4:105-10.

  • Adelson L, Sunshine I, Rushforth NB, Mankoff M.Vitreous potassium concentration as an indicator of the postmortem interval. J Forensic Sci 1963;54:503-14.

  • Adjutantis G, Coutselinis A. Estimation of the time of death by potassium levels in the vitreous humour. Forensic Sci 1972;1:55-60.

  • Agrawal RL, Gupta PC, Bhasin S, Nagar CK. Determination of the time of death by estimating potassium level in the cadaver vitreous humour. Indian J Ophthalmol 1983;31:528-31

  • Apurva Nandy Principles of Forensic Medicine, Second edition; Death and Postmortem Changes, 151-166.

  • Balabanova S, Gras V. [Forensic value of phenobarbital, calcium and magnesium determination in vitreous humor] [Article in German]. Arch Kriminol 1992;189:48-55.

  • Balasooriya BA, St Hill CA, Williams AR. The biochemistry of vitreous humour. A comparative study of the potassium, sodium and urate concentrations in the eyes at identical time intervals after death. Forensic Sci Int 1984;26: 85-91.

  • Basu Fundamentals of forensic Medicine and Toxicology;Death, 62-73.

  • Bito L, Davson H. Steady-state concentrations of potassium in the ocular fluids.Exp Eye Res 1964;76:283-97.

  • Bito LZ. Intraocular fluid dynamics. I. Steadystate concentration gradients of magnesium, potassium and calcium in relation to the sites and mechanisms of ocular cation transport processes. Exp Eye Res 1970;10:102-16.

  • Bito LZ. The physiology and pathophysiology of intraocular fluids. Exp Eye Res 1977;25 Suppl: 273-289.

  • Blumenfeld TA, Mantell CH, Catherman RL, Blanc WA. Postmortem vitreous humor chemistry in sudden infant death syndrome and in other causes of death in childhood. Am J Clin Pathol 1979;71:219-26. Bray M, Luke JL, Blackbourne BD. Vitreous humor chemistry in deaths associated with rapid chilling and prolonged freshwater immersion. J Forensic Sci 1983;28:588-93.


Abstract Views: 611

PDF Views: 0




  • Estimation of Post Mortem Interval by Means of Changes in the Eye-vitreous Humour Potassium Levels

Abstract Views: 611  |  PDF Views: 0

Authors

Deokar Ravindra
Seth G.S. Medical College , KEM Hospital, Mumbai, India
Shendarkar Ajay
Nmdvps's Dr. V.N. Pawar Maratha Vidya Prasarak Samaj's Dr. Vasantrao Pawar Medical College Hospital and Research Centre, Nashik, India

Abstract


The present study was carried out in Shri. Vasantrao Naik Government Medical College, Yavatmal. The dead bodies brought to the mortuary were used as material for collection of vitreous humour sample from the eyes of deceased. The vitreous analytes have been investigated to establish their correlationship with PMI or time since death. A significant linear correlationship, at various degrees, was seen to exist between PMI and vitreous potassium

Keywords


Potassium, Vitreous Humour, Post Mortem Interval

References