Indian Journal of Forensic Medicine & Toxicology

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Prolonged Hypotension - an Unusual Complication Following Nitrazepam Overdose


Affiliations
1 P.N.M. Hospital, Killy, Kattakada, Thiruvananthapuram, Kerala 695 572, India
2 Department of Medicine, P.N.M. Hospital, Kattakada, Thiruvananthapuram, Kerala 695572, India
     

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Nitrazepam is a long acting benzodiazepine which has been used for insomnia as well as for anxiety states. The common side effects are drowsiness and respiratory depression. We report a case of severe prolonged hypotension requiring ionotropic support following nitrazepam overdose.
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  • Oelschläger H. Chemical and pharmacologic aspects of benzodiazepines. Schweiz Rundsch Med Prax. 1989 Jul 4;78 (27-28):766-72.

  • Podhorna J; Krsiak M. (2000). “Behavioural effects of a benzodiazepine receptor partial agonist, Ro 19-8022, in the social conflict test in mice. Behavioural pharmacology. 11 (2): 143-51.

  • Acute effects of temazepam and nitrazepam on psychomotor skills and memory. Acta Pharmacol Toxicol (Copenh).1979 May;44(5):364-9.

  • Lim HC; Nigro MA, Beierwaltes P, Tolia V, Wishnow R. Nitrazepam-induced cricopharyngeal dysphagia, abnormal esophageal peristalsis and associated bronchospasm: probable cause of nitrazepam-related sudden death.1992; 14 (5): 309-14.

  • Hossmann V; Maling TJ, Hamilton CA, Reid JL, Dollery CT. (Aug 1980). Sedative and cardiovascular effects of clonidine and nitrazepam. Clin Pharmacol Ther.1980;28 (2): 167-76.


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  • Prolonged Hypotension - an Unusual Complication Following Nitrazepam Overdose

Abstract Views: 274  |  PDF Views: 0

Authors

Kiran Gopinath
P.N.M. Hospital, Killy, Kattakada, Thiruvananthapuram, Kerala 695 572, India
Rose Margaret
Department of Medicine, P.N.M. Hospital, Kattakada, Thiruvananthapuram, Kerala 695572, India
G. Vijayan
Department of Medicine, P.N.M. Hospital, Kattakada, Thiruvananthapuram, Kerala 695572, India

Abstract


Nitrazepam is a long acting benzodiazepine which has been used for insomnia as well as for anxiety states. The common side effects are drowsiness and respiratory depression. We report a case of severe prolonged hypotension requiring ionotropic support following nitrazepam overdose.

References