Indian Journal of Forensic Medicine & Toxicology

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Study of Secretors and Non-secretors in Normal Healthy Population - its Forensic Implication in Human Identification


Affiliations
1 Dept. of Physiology, S.S. Institute of Medical Sciences and Research Centre, Davangere 577 005, Karnataka, India
2 Dept. of Oral Medicine and Radiology, College of Dental Sciences, Davangere 577 004, Karnataka, India
3 Dept. of Forensic Medicine, S.S. Institute of Medical Sciences and Research Centre, Davangere 577 005, Karnataka, India
4 Department of Physiology, Rajarajeshwari Medical College, Bangalore, Karnataka, India
     

   Subscribe/Renew Journal


Blood group antigens A and B are not only confined to red cells but can be detected in other tissue cells and in body fluids. They have wide distribution and have been found in saliva, gastric juice, semen, ovarian cyst fluid, amniotic fluid and in smaller quantities in sweat,tears,bile,milk,urine etc [except CSF]. It has been established that, secretion of group specific substances is controlled by a pair of alleles Se and se. Thus, individuals can be homozygous [SeSe], heterozygous [Sese] or homozygous [sese]. The first 2 classes are called secretors and third class, non-secretor. Presence of blood and body fluids like saliva, semen etc on victims body provides important clue in crime investigation. A sample of saliva may be obtained from both the suspect as well as the victim in crimes to determine secretor status. The present study is done to determine the secretor status in 105 normal healthy subjects and to study the distribution of blood groups, secretors and non-secretors in normal healthy population, so that the knowledge of secretor status provides a useful tool in medicolegal cases for detection of suspected crime.

Keywords

Secretor, Saliva, Blood Group, Crime Detection
Subscription Login to verify subscription
User
Notifications
Font Size


  • Parikh CK. Forensic biology and serology.Textbook of Medical Jurisprudence,Forensic Medicine and Toxicology 2004. Sixth edn;CBS Publishers and Distributers,New Delhi: part 4, section 7.1.

  • Gupta YN, Gupta S, Sanyal B. Blood group specific substances in saliva of patients with cervical carcinoma.Int J Gynaecol obstet 1981; 19:83-84.

  • Apurba Nandy. Identification from trace substances and their other evidential values.Principles of Forensic Medicine 2005.2nd edn; New central book agency (P) Ltd, Calcutta: 131.

  • Godkar PB, Godkar DB .Text book of medical laboratory technology,2003.2nd edn;Bhalani Publishing House, Mumbai: 860-865.

  • Roy MN, Chatterjee JB. Some observations on secretion the secretions on the secretion of blood group substances in the body fluids of man. J.Ind.Med.Ass 1965; 45:413-417.

  • K.S. Narayana Reddy. Blood stains. The essentials of Forensic Medicine and Toxicology 2008 .27th Edition; Medical Book Company, Hyderabad: 396-398.

  • Patick AW, Collier A .An Infectious etiology of insulin dependent diabetes mellitus? Role of the secretor status.FEMS Microbial Immunol 1989; 1 (6-7):411-416.

  • Saudicani P,Hein HO, Gyntelberg F. Genetic and life style determinants of peptic ulcer. A study of 3387 men aged 54 to 74 years. The Coppenhagen Male study, Scand J Gastroenterol 1999; 34:12-17.

  • Raza MW, Balckwell CC, Molyneaux P. Association between secretor status and respiratory viral illness. BMJ 1959;1: 603-607.

  • Kathleen EB, Barbara ED,Lincoln PJ.Blood group serology. 6th edn. Edinburg London Melbourne and New York: Churchill Living stone; 1988:44-48.


Abstract Views: 301

PDF Views: 0




  • Study of Secretors and Non-secretors in Normal Healthy Population - its Forensic Implication in Human Identification

Abstract Views: 301  |  PDF Views: 0

Authors

Chandrashekhar Karpoor
Dept. of Physiology, S.S. Institute of Medical Sciences and Research Centre, Davangere 577 005, Karnataka, India
Savitha S. Shettar
Dept. of Oral Medicine and Radiology, College of Dental Sciences, Davangere 577 004, Karnataka, India
Vijayakumar B. Jatti
Dept. of Forensic Medicine, S.S. Institute of Medical Sciences and Research Centre, Davangere 577 005, Karnataka, India
Vasant Kulkarni
Department of Physiology, Rajarajeshwari Medical College, Bangalore, Karnataka, India

Abstract


Blood group antigens A and B are not only confined to red cells but can be detected in other tissue cells and in body fluids. They have wide distribution and have been found in saliva, gastric juice, semen, ovarian cyst fluid, amniotic fluid and in smaller quantities in sweat,tears,bile,milk,urine etc [except CSF]. It has been established that, secretion of group specific substances is controlled by a pair of alleles Se and se. Thus, individuals can be homozygous [SeSe], heterozygous [Sese] or homozygous [sese]. The first 2 classes are called secretors and third class, non-secretor. Presence of blood and body fluids like saliva, semen etc on victims body provides important clue in crime investigation. A sample of saliva may be obtained from both the suspect as well as the victim in crimes to determine secretor status. The present study is done to determine the secretor status in 105 normal healthy subjects and to study the distribution of blood groups, secretors and non-secretors in normal healthy population, so that the knowledge of secretor status provides a useful tool in medicolegal cases for detection of suspected crime.

Keywords


Secretor, Saliva, Blood Group, Crime Detection

References