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Preparation of Nanofibrous Mat Using Eco-Friendly, Biocompatible and Biodegradable Material


Affiliations
1 Department of Textile Chemistry Technology, Faculty of Industrial Textiles and Fashion Design, Rajamangala University of Technology Phra Nakhon, Bangkok, Thailand
2 Department of Textile Engineering, Amirkabir University of Technology, Tehran, Iran, Islamic Republic of
3 Faculty of Physics, Kharazmi University, Tehran, Iran, Islamic Republic of
4 Department of Textile Chemistry Technology, Faculty of Industrial Textiles and Fashion Design, Rajamangala University of Technology Phra Nakhon, Bangkok, Thailand
 

A novel blend of pectin/ chitosan (CS)/polyvinyl alcohol (PVA)has been prepared as a nanofibrous scaffold for skin tissue engineering and wound healing applications. Pectin has been used as an eco-friendly, non-toxic and water-soluble polymer to improve nanofibre properties. Pectin as a poly-anion polymer, in combination with chitosan polycationic polymers, creates a cross-linked poly-electrolyte complex with biocompatible properties. The CS/PVA solutions containing various concentrations of pectin are electrospun to form a 3D pectin/ CS/ PVA nano fibrous scaffold. Mechanical and antibacterial properties of the nanofibrous scaffolds are evaluated by various instrumental techniques, such as Attenuated Total Reflection-Fourier Transform Infrared, Scanning Electron Microscopy, nitrogen content and Differential Scanning Calorimetry. Mechanical properties are found to be improved and the strong antibacterial activity of the pectin/CS/PVA nano fibrous scaffold is confirmed against Escherichia coli, Staphylococcus aureus, Klebsiella and Candida albicans.

Keywords

Antibacterial Properties, Biocompatible Fibre, Biodegradable Fibre, Chitosan, Mechanical Properties, Nanofibrous, Pectin, Polyvinyl Alcohol.
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  • Preparation of Nanofibrous Mat Using Eco-Friendly, Biocompatible and Biodegradable Material

Abstract Views: 81  |  PDF Views: 72

Authors

Mojgan Razaghpour
Department of Textile Chemistry Technology, Faculty of Industrial Textiles and Fashion Design, Rajamangala University of Technology Phra Nakhon, Bangkok, Thailand
Bahareh Moazzenchi
Department of Textile Engineering, Amirkabir University of Technology, Tehran, Iran, Islamic Republic of
Farhad Pourhosseini
Faculty of Physics, Kharazmi University, Tehran, Iran, Islamic Republic of
Rattanaphol Mongkholrattanasit
Department of Textile Chemistry Technology, Faculty of Industrial Textiles and Fashion Design, Rajamangala University of Technology Phra Nakhon, Bangkok, Thailand

Abstract


A novel blend of pectin/ chitosan (CS)/polyvinyl alcohol (PVA)has been prepared as a nanofibrous scaffold for skin tissue engineering and wound healing applications. Pectin has been used as an eco-friendly, non-toxic and water-soluble polymer to improve nanofibre properties. Pectin as a poly-anion polymer, in combination with chitosan polycationic polymers, creates a cross-linked poly-electrolyte complex with biocompatible properties. The CS/PVA solutions containing various concentrations of pectin are electrospun to form a 3D pectin/ CS/ PVA nano fibrous scaffold. Mechanical and antibacterial properties of the nanofibrous scaffolds are evaluated by various instrumental techniques, such as Attenuated Total Reflection-Fourier Transform Infrared, Scanning Electron Microscopy, nitrogen content and Differential Scanning Calorimetry. Mechanical properties are found to be improved and the strong antibacterial activity of the pectin/CS/PVA nano fibrous scaffold is confirmed against Escherichia coli, Staphylococcus aureus, Klebsiella and Candida albicans.

Keywords


Antibacterial Properties, Biocompatible Fibre, Biodegradable Fibre, Chitosan, Mechanical Properties, Nanofibrous, Pectin, Polyvinyl Alcohol.

References