Passive Immunization Against Streptococcus Mutans

Dental caries is an irreversible microbial disease of the calcified tissues of teeth, which is characterized by demineralization of inorganic portion and destruction of organic substance of the tooth which often leads to cavitation. It is a multifactorial disease. Among the various microorganism Streptococcus mutans considered to be chief etiological agent. Immune therapy against this microorganism to curtail this widespread disease has gained interest. Passive antibody administration has also been examined for effects on indigenous mutans streptococci. Passive immunotherapy is of interest due to its many advantages. This review briefs on passive immunotherapy.