Efficacy and Safety of Oral Premedication on Pain after Nonsurgical Root Canal Treatment―A Review

Postoperative pain is more likely to arise within a few hours following ischolar_main canal treatment. Patients who have postoperative pain need analgesics that have fewer side effects for relieving the pain. Postoperative discomfort reduction by various preoperative means is a tried and tested method. Here, we predict symptoms that arise after treatment and try to deal with them before they begin. For those patients presenting with preoperative pain, it has been reported that up to 80% of this population will continue to report pain of different degrees even after endodontic treatment. A number of factors concerning the etiology of postoperative pain have been evaluated. The main contributing factors of pain during ischolar_main canal treatment comprises of mechanical, chemical, and microbial injuries to the pulp or periradicular tissues which are induced or exacerbated during treatment. Pretreatment analgesia is providing analgesia to patients before initiation of endodontic treatment, which can decrease the establishment of central and peripheral sensitization and has the potential to reduce postoperative pain and postoperative analgesic intake. Administration of a nonsteroidal anti-inflammatory drug before ischolar_main canal therapy will interfere with the inflammatory process before it begins; therefore, presumably decreasing postoperative pain.