Indian Journal of Public Health Research & Development

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Formocresol―Myths and Facts


Affiliations
1 Department Pedodontics and Preventive Dentistry, Sree Balaji Dental College and Hospital, Bharath University, Chennai, Tamilnadu, India
     

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Formocresol is used in endodontic therapy for pulp canal sterilization. Formocresol contains 10% formaldehyde, 35% cresol, and 15% glycerol. Various researchers have said that formocresol is effective in fixing the pulpal tissue, and it also has an impact on the enzymes and connective tissue surrounding the apices of the treated teeth. Hence, this paper reviews the history, sources, pharmacokinetics of formaldehyde and cresol, carcinogenicity, mutagenicity, clinical success and controversies regarding the safety of formocresol as medicament.

Keywords

Formocresol, Controversies, Endodontic Therapy.
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  • Formocresol―Myths and Facts

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Authors

M. Vijayakumar
Department Pedodontics and Preventive Dentistry, Sree Balaji Dental College and Hospital, Bharath University, Chennai, Tamilnadu, India
S. Amudha
Department Pedodontics and Preventive Dentistry, Sree Balaji Dental College and Hospital, Bharath University, Chennai, Tamilnadu, India
J. Aarthi
Department Pedodontics and Preventive Dentistry, Sree Balaji Dental College and Hospital, Bharath University, Chennai, Tamilnadu, India
M. Asweni
Department Pedodontics and Preventive Dentistry, Sree Balaji Dental College and Hospital, Bharath University, Chennai, Tamilnadu, India

Abstract


Formocresol is used in endodontic therapy for pulp canal sterilization. Formocresol contains 10% formaldehyde, 35% cresol, and 15% glycerol. Various researchers have said that formocresol is effective in fixing the pulpal tissue, and it also has an impact on the enzymes and connective tissue surrounding the apices of the treated teeth. Hence, this paper reviews the history, sources, pharmacokinetics of formaldehyde and cresol, carcinogenicity, mutagenicity, clinical success and controversies regarding the safety of formocresol as medicament.

Keywords


Formocresol, Controversies, Endodontic Therapy.



DOI: https://doi.org/10.37506/v10%2Fi12%2F2019%2Fijphrd%2F192359