Indian Journal of Public Health Research & Development

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Lipoxins-Resolution of Inflammation―A Review


Affiliations
1 Department of Periodontitis, Sree Balaji Dental College and Hospital, Bharath University, Chennai, Tamilnadu, India
     

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The lipoxins include lipoxin A and lipoxin B.The appearance of these molecules signals the resolution of inflammation.Lipoxins are lipoxygenase derived eicosanoids and are generated from arachidonic acid.They are highly potent, possessing biologic activity at very low concentration, and inhibit neutrophil recruitment, chemotaxis, and adhesion.

Keywords

Lipoxin, Anti-Inflammatory, Resolution of Inflammation, Anti-Fibrotic, Leukocytes, Mesangial Cells.
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  • Lipoxins-Resolution of Inflammation―A Review

Abstract Views: 458  |  PDF Views: 0

Authors

Preethe Paddmanabhan
Department of Periodontitis, Sree Balaji Dental College and Hospital, Bharath University, Chennai, Tamilnadu, India
V. Ramya
Department of Periodontitis, Sree Balaji Dental College and Hospital, Bharath University, Chennai, Tamilnadu, India
J. Bhuvaneswarri
Department of Periodontitis, Sree Balaji Dental College and Hospital, Bharath University, Chennai, Tamilnadu, India

Abstract


The lipoxins include lipoxin A and lipoxin B.The appearance of these molecules signals the resolution of inflammation.Lipoxins are lipoxygenase derived eicosanoids and are generated from arachidonic acid.They are highly potent, possessing biologic activity at very low concentration, and inhibit neutrophil recruitment, chemotaxis, and adhesion.

Keywords


Lipoxin, Anti-Inflammatory, Resolution of Inflammation, Anti-Fibrotic, Leukocytes, Mesangial Cells.



DOI: https://doi.org/10.37506/v10%2Fi12%2F2019%2Fijphrd%2F192364