Influence of Autologous Platelet Concentrates on the Dynamics of Regenerative Processes in Treatment of Trophic Ulcers of Lower Extremities

The effectiveness of the use of Autologous platelet concentrates was studied to improve the regenerative processes of trophic ulcers. The study involved 41 patients of the surgical department of “Simferopol Central Clinical Hospital” with trophic ulcers (TU) of the lower extremities of various sizes and shapes from 4 to 26 cm². In addition to the complex treatment of trophic ulcers, patients of the 1st group received topical treatment with stimulants of the regenerative process - Autologous Platelet Concentrates (APC), followed by repeated applications if necessary. According to standard approaches, 20 patients with TU were treated (group 2). The use of APC therapy in the complex treatment of TU was clinically effective. The applied method in the 1st group helped to accelerate the processes of wound repair, reduce the healing time of trophic ulcers and statistically significant decrease in the area of the wound defect compared with patients of the 2nd group were found. The use of APC therapy in the treatment of TU is clinically effective. The applied method contributed to the acceleration of wound recovery processes.