Using of Omega 3 to Reduce the Toxic Effect of Antituberculosis Therapy on Hepatorenal Function and Some of Blood Parameters of Albino Male Rats

Objective: Antituberculosis is anti-inflammatory drug used widely to treat tuberculosis, it is active drug but unfortunately causes harmful side effects on liver, kidney and blood. In the present study we used Omega 3 to reduce the side effects of this drug.

Method: The study was carried out on 40 males of albino rats. We divided the animals into four groups; control of healthy animals group, antituberculosis group, antituberculosis drug plus omega group and only omega group..Then after two months samples of blood were withdrawn from the animals for analyzing of some blood, liver and kidney parameters.

Results: Our study proved that Omega-3 can significantly reduce the toxicity of “antituberculosis drug” for some hematological, liver and kidney parameters (“ALT,AST,Urea, Creatinine”).

Conclusion: the results showed that “Omega-3” have protective characteristic to reduce the toxicity of “antituberculosis drug”.