Indian Journal of Public Health Research & Development

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Impact of Fertilization Rate on ICSI Outcome and Pregnancy Rate for Unexplained Subfertile Couples


Affiliations
1 Department of Pharmacology, Al-Kafeel University, Najaf, Iraq
2 Department of Physiology, Thi-Qar University, Iraq
3 College of Pharmacy, Telafer University, Iraq
4 Department of Urology, Kufa University, Iraq
5 College of Health and Medical Technology, University of Al-Ayen, Thi-Qar, Iraq
6 Specialized Dental Center Sumer, Thi-Qar Health Directorate, Thi-Qar, Iraq
     

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Fifty subfertility couples were involved in the present study during their attendance at the fertility clinic at Al-Sadder teaching hospital in Al-Najaf/Iraq throughout a period from January 2018 to January 2019 to undergo intracytoplasmic sperm injection (ICSI). Details history and physical examination were done for every subject participated in this study. Fertilization rate (FR) was calculated as percentage transformation of microinjected oocytes into two pronuclei. A categorical variable of FR defined based on 50% FR grouped couples; Group I with FR>50% and Group II with FR>50%. The objective of this study was to investigate the influence of fertilization rate on ICSI outcome and pregnancy rate for unexplained subfertile couples. Main results of this study revealed that there was a significant difference (p<0.05) in ICSI outcome and pregnancy rate between different study groups. With increasing fertilization rate, there was an increase in the ICSI outcome and the pregnancy rate. It was concluded that increased fertilization rate have a positive impact on the ICSI outcome and pregnancy rate for unexplained subfertile couples.

Keywords

Intracytoplasmic Sperm Injection, Fertilization, Fertilization Rate.
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  • Impact of Fertilization Rate on ICSI Outcome and Pregnancy Rate for Unexplained Subfertile Couples

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Authors

Saad Mashkoor Waleed Al-Zaiyadi
Department of Pharmacology, Al-Kafeel University, Najaf, Iraq
Abdulhasan Mahdi Salih
Department of Physiology, Thi-Qar University, Iraq
Iqbal Ajrash Sabr
College of Pharmacy, Telafer University, Iraq
Sahib Yahia Al-Murshidi
Department of Urology, Kufa University, Iraq
Ali B. Roomi
College of Health and Medical Technology, University of Al-Ayen, Thi-Qar, Iraq
Athraa Mohammed Dheyaa
Department of Pharmacology, Al-Kafeel University, Najaf, Iraq
Mohammed Kadhim Al-koofee
Specialized Dental Center Sumer, Thi-Qar Health Directorate, Thi-Qar, Iraq

Abstract


Fifty subfertility couples were involved in the present study during their attendance at the fertility clinic at Al-Sadder teaching hospital in Al-Najaf/Iraq throughout a period from January 2018 to January 2019 to undergo intracytoplasmic sperm injection (ICSI). Details history and physical examination were done for every subject participated in this study. Fertilization rate (FR) was calculated as percentage transformation of microinjected oocytes into two pronuclei. A categorical variable of FR defined based on 50% FR grouped couples; Group I with FR>50% and Group II with FR>50%. The objective of this study was to investigate the influence of fertilization rate on ICSI outcome and pregnancy rate for unexplained subfertile couples. Main results of this study revealed that there was a significant difference (p<0.05) in ICSI outcome and pregnancy rate between different study groups. With increasing fertilization rate, there was an increase in the ICSI outcome and the pregnancy rate. It was concluded that increased fertilization rate have a positive impact on the ICSI outcome and pregnancy rate for unexplained subfertile couples.

Keywords


Intracytoplasmic Sperm Injection, Fertilization, Fertilization Rate.