Clinical Study for Testosterone, Progesterone and Oxidative Stress During Phases of Menstrual Cycle in Women with Bronchial Asthma

This study aims to evaluate the hormones (testosterone (T) and progesterone (P)) and oxidative stress malondialdehyde (MDA), ceruloplasmin (CP) and transferrin (Tf) during Phases of menstrual cycle (follicular and luteal phase) in females with asthmatic. Included (70) women patients with bronchial asthma without taking contraceptive pills aged (14-45 years). Included (70) women as a control group supposed healthy without taking contraceptive pills with the same age in this study. The results showed a significant decline in levels of the Progesterone (P) and Testosterone (T) and significantly higher in levels of the (MDA) and (CP) in all patients in both follicular phase as well in the luteal phase in compared with control group in the follicular and luteal phase respectively (P ≤ 0.05).We did not notice any significant difference in concentration of serum TF in all patients in both follicular phase as well in the luteal phase in comparison with control group in the follicular phase and luteal phase respectively (P ≤ 0.05).Showed serum levels of Testosterone and Progesterone significantly higher in all patients in the luteal phase when comparison with all patients in the follicular phase (P ≤ 0.05). We did not notice any significant difference in (MDA, CP and TF) levels in all patients in the luteal phase when comparison with all patients in the follicular phase (P ≤ 0.05).