Evaluation of Hepatoprotective Activities of Pomegranate Crude Extract in Steatosis Induced Obese Mice

The current study is aimed to reconnoiter the effective role of Pomegranate Crude Extract (PCE) in the liver tissues of castrated male mice, for this 45 male Albino mice [4 weeks] aged, were distributed in to 3 groups N = 15 for each group. From a period February to May 2018. The results showed there were histological variations were detected in the liver of induced castrated mice demonstrated by the form of disturbed hepatic structures, reduction in sinusoids, cytoplasmic vacuolation in hepatocytes, accumulation of lipid [microvesicular steatosis & macrovesicular steatosis], these variations related with inflammatory of lymphocytes in addition, all these histological changes were less pronounced in the group that treated with (PCE), this study was concluded that [PCE] has marked improving effects against liver steatosis complications. For this reason, we recommend that you use the pomegranate fruit or its juice in the (daily food table) against the increase in hyperlipidemia.