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Role of Free Radicals in Cellular Signaling: A Review
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Reactive oxygen species (ROS) were once considered to be deleterious agents, contributing to a vast range of pathologies. Both their damaging and beneficial effects are initiated when they target distinct molecules and consequently begin functioning as part of complex signal-transduction pathways. The recognition of ROS as signaling mediators has driven a wealth of research into their roles in both normal and pathophysiological states. The present review assesses the outline of current perspectives on redox-signaling mechanisms.
Keywords
Reactive Oxygen Species, Oxidative Stress, Nitric Oxide.
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