Indian Journal of Public Health Research & Development

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Review on Platelet Rich Fibrin and Case Report on Management of Large Periapical Lesion


Affiliations
1 Reader, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai, Tamilnadu, India
2 Final Year PG Student, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai, Tamilnadu, India
3 Professor, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai, Tamilnadu, India
     

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Platelet Rich Fibrin consists of an autologous leukocyte-platelet-rich fibrin matrix, composed of a tetra molecular structure, with platelets, leukocytes and stem cells within it, which acts as a biodegradable scaffold that favors microvascularization and is able to guide epithelial cell migration to its surface. This case report describes about the management of large periapical lesions with surgical approach and PRF placement and a non-surgical approach.

Keywords

Platelet Rich Fibrin, Leukocytes, Scaffold.
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  • Review on Platelet Rich Fibrin and Case Report on Management of Large Periapical Lesion

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Authors

Geethapriya Nagarajan
Reader, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai, Tamilnadu, India
Parthasarathy Rajasekar
Final Year PG Student, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai, Tamilnadu, India
Selvakumar Gold Pearlin Mary Newbegin
Reader, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai, Tamilnadu, India
Venkatesh Alagarsamy
Professor, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai, Tamilnadu, India

Abstract


Platelet Rich Fibrin consists of an autologous leukocyte-platelet-rich fibrin matrix, composed of a tetra molecular structure, with platelets, leukocytes and stem cells within it, which acts as a biodegradable scaffold that favors microvascularization and is able to guide epithelial cell migration to its surface. This case report describes about the management of large periapical lesions with surgical approach and PRF placement and a non-surgical approach.

Keywords


Platelet Rich Fibrin, Leukocytes, Scaffold.