Combined Exercise Effects on Lipid Profiles in Hypertensive Patients

Objective: The purpose of the study was to examine combined aerobic and resistance exercise training effect on lipid profiles in hypertensive patients. Method: A total of forty‑six hypertensive patients aged between 31 and 45 years were randomly assigned into two groups: control group (n=23) and exercise group (n=23). Total cholesterol (TC), high density lipoprotein cholesterol (HDL‑c), low density lipoprotein cholesterol (LDL‑c), and triglycerides (TGs) data were collected at baseline and after 16 weeks of the study period. Analyses of within group and between group comparisons were done using paired sample t‑test and independent sample t‑test, respectively. Results: Pre‑intervention data of TC, LDL‑c, TGs, and HDL‑c were homogeneous compared with groups (P>0.05). After completion of the study significant between group mean change difference was found in TC (‑7.2 mg/dl; P=0.0001), LDL‑c (‑10 mg/dl; P=0.0001), TGs (‑14.3 mg/dl; P=0.0001), and in HDL‑c (3.8 mg/ dl; P=0.001). In EG participants performed combined aerobic and resistance exercise training. Conclusions: Combined aerobic and resistance exercise training significantly reduced TC, LDL‑c, TGs and significantly increased HDL‑c levels in hypertensive patients. Public awareness promotion should be designed and implemented by concerned bodies for hypertensive patients to realize the importance of combined exercise trainings and thereby increases their adherence to exercise programs. Trial Registration: Clinicaltrials.gov Identifier: NCT03029767 on 20/01/2017.