Association of Diabetes Mellitus and Estrogen Hormone Levels with Vaginal Candidiasis

Objectives: The aim of this study was to investigate the association of diabetes mellitus and estrogen hormone levels with vaginal candidiasis. Method: A cross sectional comparative study was used on 2018 from women of childbearing age (20‑35 years) and one‑year oral contraceptive who came to the obstetric polyclinic who conducted visual inspection with acetic acid (VIA) in Bhayangkara Hospital Polyclinic, Padang Pasir and Nanggalo Primary Health Care Padang City, West Sumatera Province, Indonesia. We recruited 58 respondents with consecutive sampling technique. Vaginal candidiasis was measured using vaginal secretions and microscopic laboratory test. Diabetes mellitus was measured using fast blood glucose and estrogen hormone levels measured with blood sample analysis using Enzyme‑Linked Immunosorbent Assays (ELISA). Chi‑square test and independent sample T test were used to data analysis, P value < 0.05 was considered as statistically significant association. Data were processed using IBM SPSS Statistics 24.0. Results: Diabetes mellitus was associated with vaginal candidiasis (p<0.05). There was statistically significant mean difference of estrogen hormone levels with vaginal candidiasis, estrogen hormone levels with vaginal candidiasis were 143.39 pg/ml higher than not vaginal candidiasis were 60.99 pg/ml. Conclusion: This analysis confirmed association of diabetes mellitus and estrogen hormone levels with vaginal candidiasis.