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Saliva as a Biomarker for Sysytemic Diseases


Affiliations
1 Post Graduate Student, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, India
2 Professor, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, India
3 Reader, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, India
4 Professor and Head of the Department, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, India
     

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Human whole mouth saliva (WMS) is secreted by salivary glands, namely parotid, submandibular/sublingual and other minor glands of the oral cavity. The human saliva consists of various proteins and peptides which serve as diagnostic aids in detection of various contagious and organ related diseases. Saliva can be used to detect various systemic and oral diseases. In any disease early diagnosis helps in proper treatment planning and better prognosis. Saliva has a great potential as a diagnostic fluid and offers advantage over serum and other biological fluids by an economic and non- invasive collection method for monitoring of systemic health and disease progression.This review examines the diagnostic application of saliva for systemic diseases.

Keywords

Saliva, Diagnostic Fluid, Biomarker, Systemic Disease.
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  • Saliva as a Biomarker for Sysytemic Diseases

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Authors

R. Hariharan
Post Graduate Student, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, India
N. Aravindha Babu
Professor, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, India
N. Anitha
Reader, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, India
K. M. K. Masthan
Professor and Head of the Department, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, India

Abstract


Human whole mouth saliva (WMS) is secreted by salivary glands, namely parotid, submandibular/sublingual and other minor glands of the oral cavity. The human saliva consists of various proteins and peptides which serve as diagnostic aids in detection of various contagious and organ related diseases. Saliva can be used to detect various systemic and oral diseases. In any disease early diagnosis helps in proper treatment planning and better prognosis. Saliva has a great potential as a diagnostic fluid and offers advantage over serum and other biological fluids by an economic and non- invasive collection method for monitoring of systemic health and disease progression.This review examines the diagnostic application of saliva for systemic diseases.

Keywords


Saliva, Diagnostic Fluid, Biomarker, Systemic Disease.