Estimation of Red Blood Cell Parameters and Serum Prohepcidin Level in Generalised Chronic Periodontitis Patients Before and After Non-Surgical Periodontal therapy

Background: The Anaemia of chronic disease (ACD) is a prevalent, poorly understood condition that afflicts patients with a wide variety of diseases, including infections, malignancies and rheumatologic disorders.

Materials and Method: 40 patients 20-65 years of age with chronic periodontitis were assessed before and after periodontal therapy for Hb, ESR, Erythrocyte count, MCV, MCH, MCHC and PROHEPCIDIN (ELISA).

Results: A significant (p<.000) increase in RBC (4.581) and Hb (12.77) values were estimated after SRP compared to baseline. Prohepcidin levels decreased insignificantly after SRP. Tailed t test results shows significant correlation at the 0.01 level between RBC parameters but no significance between probing depth or prohepcidin values with RBC parameters.

Conclusion: The results conclude that reduction in periodontal inflammation by scaling and ischolar_main planning improves RBC count and hemoglobin level significantly Prohepcidin levels decreases with periodontal treatment but rather insignificantly.