Reported Adverse Drug Reactions in Off–Label Use of Azathioprine in Dermatology:A Review

The skin is one of the largest organs in the human body. Majority of skin diseases requires lifelong treatments since they are chronic in nature. Thereby, appropriate diagnosis by the physicians and rational prescription of drugs becomes a vital component of drug therapy. ADR monitoring is considered to be mandatory as they become severe and potentially life-threatening. Primarily, in off-label setting, patients are treated with drugs which are not registered for that specific indication. Dermatologists have been at the forefront of the application of azathioprine and have thus been using the immunosuppressant for treating patients over several years.