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The Effect of Different Doses of Green Tea Extract on Hematological and Biochemical Parameters in Adult Male Rats
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This investigates the effects of various concentrations of continuous drinking of green tea in rats. (24) male rats are randomly categorized into four groups: control, which does not receive green tea, GTE5, GTE10 and GTE20 (receive 5g, 10g and 20g GTE, respectively). In hematological parameters analysis, there are no significant variation (p>0.05) in the RBC, MCHC and platelet among all groups. Furthermore, Control group presented a considerable decrease (p <0.05) in HB, HTC, MCV and MCH as compared with GTE5, GTE10 and GTE20. The biochemical analysis, control and GTE5 groups had high significant decrease (p<0.05) in glucose level as compared with GTE10 and GTE20 groups. Analysis of albumin and globulin, control and GTE5 groups had a significant decrease (p<0.05) higher than that of GTE10 and GTE20 groups. On the other hand, GTE20 group revealed a highly significant increase variation (p<0.05) in total protein than the control, GTE5 and GTE10 groups. In the control group showed a significant increase (p <0.05) in values of AST, ALT and ALK as compared with other groups. Therefore, it is recommended that using green tea for a long period leads to inhibition of the free oxygen radical damages in the liver and erythrocyte.
Keywords
Green tea, Liver enzymes, Glucose, total protein
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