Multimodal Hyperspectroscopy for Detection of Cervical Neoplasia

Objective:To provide a prospective evaluation of the sensitivity and specificity of MHS as a new test for detection of high grade cervical dysplasia.

Method:203 women previously screened with liquid based cytology were evaluated with multimodal hyperspectroscopy (MHS), colposcopy and biopsy samples taken for histopathology.

Results: Sensitivity of MHS cervical scan for high grade intraepithelial neoplasia (CIN) 2+ was 86.6% and Specificity was 57.9%

Conclusions: MHS cervical scan is a noninvasive modality for detection of high grade cervical neoplasia with good efficacy.