Antibacterial and Antibiofilm Activity of Aqueous Extract and Essential Oil of Origanummajorana and their Activity on Some Physiological Parameters of Blood in the Male of White Rats

The aim of this study was to detect the influence (aqueous extract and essential oil) of Origanummajorana on the growth of Staphylococcus aureus, Enterococcus, E.coli, Klebsiella pneumonia, Proteus mirabilis, Salmonellatyphi, Enterobacter, Acinetobacterbaumanniiand Pseudomonas aeruginosa. Also, this study aimed to detection the influence of essential oil of Origanummajorana(which gave a higher influence on bacterial growth) on biofilm information. Also this study aimed to detection the influence of essential oil of Origanummajorana on some physiological parameters of blood in a male of white rats.

This study showed the essential oil Origanummajorana was a higher effect than aqueous extract. This study showed the ability of bacteria to formation of biofilm and biofilm inhibitors by essential oil of Origanummajorana. The results of the antibiotic sensitivity test showed some of the bacteria isolates were highly resistant to the antibiotic; therefore,it is considered multidrug-resistance (MDR). The results of the effect essential oil of Origanummajorana in vivo showed variation in values in some physiological parameters of blood in the male of rats