Pharmacological Activities and Chemical Constituents and of Bryonia Dioica L.:A Review

Bryonia is one of the genera belong the Cucurbitaceae family (gourd family). Bryonia dioica distribute in Western Europe,this plant flowering in May as small, greenish and three or four flowers together in small cluster the stamens and pistils are found separated therefore consider a dioecious plant–growth as separate plant into (male and female).The phytochemical constituents of Leavesare Luteolin, flavonoids (kaempferol),. alkaloids, Glycosides, phenol steroids, Carbohydrates, anthraquinoine and terpenoids, while the part used of this plant (Roots)are Kempferol 3, 7-di-O-rhamnoside, polyphenols, sterols, triterpenes, alkaloids, heterosides-c, carbohydrates, saponins, terpenoids, flavonoids, tannins, alkaloids, quinones, reducing sugar and coumarin . The fruits containing triterpene, glucosides, calcium oxalate crystals and the flowers arePhenolic acid and flavonoids . The biological activity and pharmacological uses of all plant parts of B.dioica are antinociceptive effects, antimicrobial activities, antioxidant activity,hepatoprotective activity, Anticancer activity, hypercholesterolemia, diabetes and fertility disorders.