Indian Journal of Public Health Research & Development

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

COX2 Inhibitory activity of Abutilon indicum-In Invitro Study


Affiliations
1 Undergraduate Student, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, India
2 Associate Professor, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, India
3 Professor, Department of Pedodontics & Preventive Dentistry, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, India
4 Professor, Department of Public Health Dentistry, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, India
     

   Subscribe/Renew Journal


Aim: To analyse the COX2 inhibitory activity of Abutilon indicum.

Objective: The main objective of this study is to analyse the COX2 inhibitory activity of Abutilon indicum.

Background: Prostaglandins are important mediators of the body’s response to pain and inflammation, and are formed from essential fatty acids found in cell membranes. This reaction is catalysed by cyclooxygenase, a membrane associated enzyme in two isoforms - COX-1 and COX-2. Abutilon indicum ,commonly known as the Indian mallow is well known for its therapeutic values and further study of its COX-2 inhibitory activity is beneficial.

Conclusion: Medicinal plants and shrubs which have little or no side effects have to be further investigated. Further study on its COX-2 inhibition will increase its therapeutic value also as an anti-inflammatory with added benefits


Keywords

Ethnomedicinal, Anti-Arthritic, COX2 Inhibition, Medicinal Uses, Prostaglandin.
Subscription Login to verify subscription
User
Notifications
Font Size


Abstract Views: 132

PDF Views: 0




  • COX2 Inhibitory activity of Abutilon indicum-In Invitro Study

Abstract Views: 132  |  PDF Views: 0

Authors

C. Cinthura
Undergraduate Student, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, India
Lakshmi Thangavelu
Associate Professor, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, India
S. Rajeshkumar
Associate Professor, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, India
Deepa Gurunadhan
Professor, Department of Pedodontics & Preventive Dentistry, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, India
R. Pradeep Kumar
Professor, Department of Public Health Dentistry, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, India
Anitha Roy
Associate Professor, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, India

Abstract


Aim: To analyse the COX2 inhibitory activity of Abutilon indicum.

Objective: The main objective of this study is to analyse the COX2 inhibitory activity of Abutilon indicum.

Background: Prostaglandins are important mediators of the body’s response to pain and inflammation, and are formed from essential fatty acids found in cell membranes. This reaction is catalysed by cyclooxygenase, a membrane associated enzyme in two isoforms - COX-1 and COX-2. Abutilon indicum ,commonly known as the Indian mallow is well known for its therapeutic values and further study of its COX-2 inhibitory activity is beneficial.

Conclusion: Medicinal plants and shrubs which have little or no side effects have to be further investigated. Further study on its COX-2 inhibition will increase its therapeutic value also as an anti-inflammatory with added benefits


Keywords


Ethnomedicinal, Anti-Arthritic, COX2 Inhibition, Medicinal Uses, Prostaglandin.