Indian Journal of Public Health Research & Development

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A one Year Study of the Adequacy of Primary Prophylaxis in Prevention of Glucocorticoid-induced Osteoporosis in Rural Western Uttar Pradesh


Affiliations
1 Department of Pediatrics, Saraswathi Institute of Medical Sciences, Hapur, Ghaziabad, U.P., India
2 Department of Medicine, Saraswathi Institute of Medical Sciences, Hapur, Ghaziabad, U.P, India
3 Department of Orthopedics, Saraswathi Institute of Medical Sciences, Hapur, Ghaziabad, U.P., India
     

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Introduction: Fragility fractures are well known&serious complication of long-term treatment with corticosteroids. Glucocorticoid-induced osteoporosis (GIOP) is characterized by rapid bone loss and increased fracture risk in the early stages of beginning of therapy and is amenable to proper preventive measures. Thus, glucocorticoid-induced bone loss should be treated aggressively. The aim of this study is to probe the adequacy of primary prophylaxis for glucocorticoid-induced osteoporosis (GIOP) in patients taking long-term steroids.

Methods: A retrospective study was conducted in our institute to assess treating doctor's awareness and preventive measures taken during treatment against GIOP. Hospital records of patients receiving > 7.5 mg/day of oral steroids for > 3 months were studied and relevant data was collected. Primary preventive measures instituted against GIOP were noted and the data was analyzed.

Results: Two hundred and three patients, 121 females and 82 males, fulfilling the inclusion criteria were included in this study. Of the 203 patients, 61 did not receive any prophylaxis, 97 received inadequate prophylaxis and only 45 were given appropriate prophylaxis.

Conclusions: The awareness about instituting primary preventive measures against GIOP among treating doctors is highly unsatisfactory. There is an urgent need to increase awareness and knowledge of GIOP management. There are effective strategies for prevention and treatment of GIOP&these should be used aggressively in such patients.


Keywords

Steroids, Glucocorticoid-Induced Osteoporosis (GIOP), Prophylaxis
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  • A one Year Study of the Adequacy of Primary Prophylaxis in Prevention of Glucocorticoid-induced Osteoporosis in Rural Western Uttar Pradesh

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Authors

Bhawna Kohli
Department of Pediatrics, Saraswathi Institute of Medical Sciences, Hapur, Ghaziabad, U.P., India
Anil Kumar Kem
Department of Medicine, Saraswathi Institute of Medical Sciences, Hapur, Ghaziabad, U.P, India
Rajesh Bhatia
Department of Orthopedics, Saraswathi Institute of Medical Sciences, Hapur, Ghaziabad, U.P., India

Abstract


Introduction: Fragility fractures are well known&serious complication of long-term treatment with corticosteroids. Glucocorticoid-induced osteoporosis (GIOP) is characterized by rapid bone loss and increased fracture risk in the early stages of beginning of therapy and is amenable to proper preventive measures. Thus, glucocorticoid-induced bone loss should be treated aggressively. The aim of this study is to probe the adequacy of primary prophylaxis for glucocorticoid-induced osteoporosis (GIOP) in patients taking long-term steroids.

Methods: A retrospective study was conducted in our institute to assess treating doctor's awareness and preventive measures taken during treatment against GIOP. Hospital records of patients receiving > 7.5 mg/day of oral steroids for > 3 months were studied and relevant data was collected. Primary preventive measures instituted against GIOP were noted and the data was analyzed.

Results: Two hundred and three patients, 121 females and 82 males, fulfilling the inclusion criteria were included in this study. Of the 203 patients, 61 did not receive any prophylaxis, 97 received inadequate prophylaxis and only 45 were given appropriate prophylaxis.

Conclusions: The awareness about instituting primary preventive measures against GIOP among treating doctors is highly unsatisfactory. There is an urgent need to increase awareness and knowledge of GIOP management. There are effective strategies for prevention and treatment of GIOP&these should be used aggressively in such patients.


Keywords


Steroids, Glucocorticoid-Induced Osteoporosis (GIOP), Prophylaxis

References