Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Evaluation of Drug Therapy in Cataract Surgery at Saraswathi Institute of Medical Sciences, Ghaziabad, U.P., India


Affiliations
1 Department of Pharmacology, Saraswati Institute of Medical Sciences, Hapur, Ghaziabad, U.P., India
2 Department of Ophthalmology, Saraswati Institute of Medical Sciences, Hapur, Ghaziabad, U.P., India
3 Department of Biochemistry, Saraswati Institute of Medical Sciences, Hapur, Ghaziabad, U.P., India
4 Department of Pharmacology of Saraswati Institute of Medical Sciences, Hapur, Ghaziabad, U.P., India
     

   Subscribe/Renew Journal


Objective: To study the prescribing pattern in cataract surgery patients in SIMS, for evaluation of their pharmacoepidemiology.

Material and methods: A retrospective study was conducted in the department of Pharmacology in collaboration with the department of Ophthalmology for a period of one year. Total 720 patients were analysed. Utilisation pattern of drugs like dosages form, route, frequency of administration and duration of therapy in preoperative, intraoperative and postoperative were audited. Drug prescription versus therapeutic indication was also evaluated.

Result: Different antibiotics mostly Fluoroquinolones, (like moxifloxacine (71.11%), gatifloxacine (16.66%), ofloxacin (4.16%) and, antiinflammatory drugs-bromofenac (54.27%), flurbiprofen (45.27%) and mydriatic-cucloplegic agents were prescribed.

Conclusion: The prescription was logical in respect of therapeutic indication. But in view of cost Moxifloxacin and Bromofenac could have been replaced by cheaper antibiotics and antiinflammtory drugs as Ofloxacin and Flurbiprofen.


Subscription Login to verify subscription
User
Notifications
Font Size


  • Hooper D. Quinolones. In: Mandell GL, Bennett JE, Dolin R. Mandell, 5thed. Philadelphia: Churchill Livingstone, 2000:404–23.
  • Hooper DC, Wolfson JS. 2d ed. Washington, D.C.: American Society for Microbiology, 1993:53–7.
  • Hooper DC. Drugs. 1999;58(suppl 2):6–10.
  • Turnidge J. . Drugs. 1999;58(suppl 2):29–36.
  • Hackbarth CJ, Chambers HF, Sande MA. Antimicrob Agents Chemother. 1986;29:611–3.
  • Walker RC. The fluoroquinolones. Mayo Clin Proc. 1999;74:1030–1037.
  • Alghasham AA, Nahata M. Ann Pharmacother. 1999;33:48–60.
  • Owens RC Jr, Ambrose PG. Med Clin North Am. 2000;84:1447–69.
  • Hooper DC. Clin Infect Dis. 2000;30:243–54.
  • Ambrose PG, Owens RC . Conn Med. 1997;61:269–72.
  • Kaur, I.P. and Smitha. R., dope Develop. Ind. Pharm., 2002 28. 353.
  • Keistea, J.C., Cooper, E.R., Missel, P.J., Long, J.C. and Hager, D.F. J. Pharm. Sci, 1991, 80,50.
  • Khopade, A.J. and Jain, N.K., Pharmazie, 19%. 50, 812.
  • Kumar, S., Haglund, B.O. and Himmelstein, K.J., J. Ocul. Pharmcol., 1994,10,47.
  • Kurz, D. and Ciullla, T.A., Ophthalmic Clin. North. Amer.. 2002,15.405.
  • Latorre F. and Nicolal, A.P., doctor prescribed drugs Exp, Clin, Res.. 1998, 24, 153.
  • Lee, V.H.L. and Robinson, J.R., J. Ocul. Pharmacol., 1986, 2, 67.
  • Lin. H.R. and Sung. K.C., J. Contol. release, 2000, 69, 379.
  • lnduPal. K. and Meenakshi, K., dope Develop. Ind. Pharm., 2002, 473.
  • Marshall. W.S. and Klyee, S.D., J. membrane layer Biol., 1983, 73, 275.
  • Meseuger, G., Gumy, R., Buri, P., Rozier, A. and Plazonnet, B., Int. J. Pharm., 1993, 95, 229.
  • Middleton, D.L, Leung, S.H.S. and Robinson, J.R., In; Lenaerts,V and Gummy, R., Eds., Bioadhesive dope Delivery Systems, CRC Press, Boca Raton., 1990. 203.
  • Monem, A.S, Ali, FM. and Ismail. M W .Int. J. Pherm., 2000 198, 20.
  • Nagarsenker, M.S., Londhe, VY. and Nadkarni. G D. Int. J. Pharm., 1999, 190, 63.
  • Rathore K.S., Nema R.K., “Management of Glaucoma: a review” worldwide diary of Pharm Tech Research, Vol.1, No.3, pp, July-Sept. 2009.

Abstract Views: 297

PDF Views: 0




  • Evaluation of Drug Therapy in Cataract Surgery at Saraswathi Institute of Medical Sciences, Ghaziabad, U.P., India

Abstract Views: 297  |  PDF Views: 0

Authors

Sunita Singh
Department of Pharmacology, Saraswati Institute of Medical Sciences, Hapur, Ghaziabad, U.P., India
Vikrant Sharma
Department of Ophthalmology, Saraswati Institute of Medical Sciences, Hapur, Ghaziabad, U.P., India
Yogesh Rai
Department of Biochemistry, Saraswati Institute of Medical Sciences, Hapur, Ghaziabad, U.P., India
Vivek Singh
Department of Pharmacology of Saraswati Institute of Medical Sciences, Hapur, Ghaziabad, U.P., India

Abstract


Objective: To study the prescribing pattern in cataract surgery patients in SIMS, for evaluation of their pharmacoepidemiology.

Material and methods: A retrospective study was conducted in the department of Pharmacology in collaboration with the department of Ophthalmology for a period of one year. Total 720 patients were analysed. Utilisation pattern of drugs like dosages form, route, frequency of administration and duration of therapy in preoperative, intraoperative and postoperative were audited. Drug prescription versus therapeutic indication was also evaluated.

Result: Different antibiotics mostly Fluoroquinolones, (like moxifloxacine (71.11%), gatifloxacine (16.66%), ofloxacin (4.16%) and, antiinflammatory drugs-bromofenac (54.27%), flurbiprofen (45.27%) and mydriatic-cucloplegic agents were prescribed.

Conclusion: The prescription was logical in respect of therapeutic indication. But in view of cost Moxifloxacin and Bromofenac could have been replaced by cheaper antibiotics and antiinflammtory drugs as Ofloxacin and Flurbiprofen.


References