Indian Journal of Public Health Research & Development

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Glycemic Control and Pulmonary Function Tests in Type 2 Diabetes Mellitus Patients: do they Correlate?


Affiliations
1 Dept. of Physiology, J.S.S. Medical College, Mysore, Karnataka, India
2 Dept of Medicine, J.S.S. Medical College, Mysore, Karnataka, India
     

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Diabetes is a multisystem disorder accompanied by widespread biochemical, morphological and functional abnormalities which may precipitate certain complications that affect the renal, cardiovascular, neural system, liver, skin and tissues like collagen and elastic fibers. This study was undertaken to find out the correlation between glycemic control and pulmonary function tests(PFT).

Study group consists of 90 patients who were age, sex, height and weight matched. PFT were measured by Medspiror. Fasting blood sugar(FBS),Postprandial blood sugar(PPBS), Glycosylated haemoglobin (HbA1C) levels were recorded. The data was statistically analysed. It showed that with the worsening of glycemic control there was decrease across all the PFT parameters.

Normal lung mechanisms and gas exchange are influenced by integrity of pulmonary connective tissue and microvasculature. Hyperglycemia causes glycosylation of lung collagen and hence less compliant lung parenchyma leading to restrictive lung changes.


Keywords

Glycemic Control, Pulmonary Function Tests, Glycosylation, Restrictive Lung Pathology
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  • Glycemic Control and Pulmonary Function Tests in Type 2 Diabetes Mellitus Patients: do they Correlate?

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Authors

Kanya Kumari
Dept. of Physiology, J.S.S. Medical College, Mysore, Karnataka, India
S M Nataraj
Dept. of Physiology, J.S.S. Medical College, Mysore, Karnataka, India
H S Devaraj
Dept of Medicine, J.S.S. Medical College, Mysore, Karnataka, India

Abstract


Diabetes is a multisystem disorder accompanied by widespread biochemical, morphological and functional abnormalities which may precipitate certain complications that affect the renal, cardiovascular, neural system, liver, skin and tissues like collagen and elastic fibers. This study was undertaken to find out the correlation between glycemic control and pulmonary function tests(PFT).

Study group consists of 90 patients who were age, sex, height and weight matched. PFT were measured by Medspiror. Fasting blood sugar(FBS),Postprandial blood sugar(PPBS), Glycosylated haemoglobin (HbA1C) levels were recorded. The data was statistically analysed. It showed that with the worsening of glycemic control there was decrease across all the PFT parameters.

Normal lung mechanisms and gas exchange are influenced by integrity of pulmonary connective tissue and microvasculature. Hyperglycemia causes glycosylation of lung collagen and hence less compliant lung parenchyma leading to restrictive lung changes.


Keywords


Glycemic Control, Pulmonary Function Tests, Glycosylation, Restrictive Lung Pathology

References