Indian Journal of Public Health Research & Development

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Correlation of C-Reactive Protein with Body Mass Index and Blood Pressure in Young Adult North Indian Hypertensive Males-a Prospective Study


Affiliations
1 Department of Physiology, Subharti Medical College, N H-58 Meerut-250005, India
2 Department of Microbiology, Subharti Medical College, Meerut, India
3 Department of Medicine, Subharti Medical College, Meerut, India
4 Department of Physiology, Subharti Medical College, Meerut, India
5 Department of Biostatistics, Subharti Medical College, Meerut, India
     

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Background & Objectives: High blood pressure has been associated with elevated C-reactive protein (CRP), a possible marker of vascular inflammation. The aim of this study was to assess the interrelationship between blood pressure and CRP in young adult north Indian males.

Method: A total of 30 patients with mild to moderate essential hypertension in the age group of 25- 40 years were enrolled for the study. Patients with history of secondary or malignant hypertension were excluded. Age and sex matched healthy normotensive subjects (n=35) were taken as control. The parameters studied were BMI, Systolic (SBP), diastolic (DBP) blood pressure and CRP. C-reactive protein was measured by RHELAX CRP slide test. Statistical analysis was done by using Karl-Pearson correlation coefficient and Student's unpaired t test.

Results: We have observed significant differences (P0.01) association between blood pressure and CRP levels in the study group.

Conclusion: Further studies are needed to explore the relationship between blood pressure and CRP using highly sensitive assays as a major screening test in the prediction, diagnosis and management of essential hypertension.


Keywords

BMI, Blood Pressure, C-Reactive Protein, Young Indian Adults
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  • Correlation of C-Reactive Protein with Body Mass Index and Blood Pressure in Young Adult North Indian Hypertensive Males-a Prospective Study

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Authors

Kiran Singh
Department of Physiology, Subharti Medical College, N H-58 Meerut-250005, India
Anita Pandey
Department of Microbiology, Subharti Medical College, Meerut, India
Tanuraj Sirohi
Department of Medicine, Subharti Medical College, Meerut, India
Rajesh Misra
Department of Physiology, Subharti Medical College, Meerut, India
Rupesh Tewari
Department of Biostatistics, Subharti Medical College, Meerut, India

Abstract


Background & Objectives: High blood pressure has been associated with elevated C-reactive protein (CRP), a possible marker of vascular inflammation. The aim of this study was to assess the interrelationship between blood pressure and CRP in young adult north Indian males.

Method: A total of 30 patients with mild to moderate essential hypertension in the age group of 25- 40 years were enrolled for the study. Patients with history of secondary or malignant hypertension were excluded. Age and sex matched healthy normotensive subjects (n=35) were taken as control. The parameters studied were BMI, Systolic (SBP), diastolic (DBP) blood pressure and CRP. C-reactive protein was measured by RHELAX CRP slide test. Statistical analysis was done by using Karl-Pearson correlation coefficient and Student's unpaired t test.

Results: We have observed significant differences (P0.01) association between blood pressure and CRP levels in the study group.

Conclusion: Further studies are needed to explore the relationship between blood pressure and CRP using highly sensitive assays as a major screening test in the prediction, diagnosis and management of essential hypertension.


Keywords


BMI, Blood Pressure, C-Reactive Protein, Young Indian Adults

References