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Spectrum of Benign Upper Gastro Intestinal Lesions Diagnosed by Endoscopic Examination Followed by Biopsy


Affiliations
1 Dept of Pathology, Navodaya Medical College (NMC), Raichur, Karnataka, India
2 Dept. of Pathology, Goa Medical College (GMC), Bambolim, Goa, India
3 Dept. of Pathology, GMC, Bambolim, Goa, India
     

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Background: Upper gastrointestinal lesions run the gamut from inflammatory lesions to carcinoma. Endoscopy has greatly facilitated biopsy diagnosis. Present study reveals spectrum of benign upper gastro intestinal lesions obtained by endoscopic biopsy.

Aims:

1) To study types of lesions

2) Comparison with Indian and Western literature.

Setting & Design: It is observational study. Patients with upper gastro-intestinal complaints were subjected to endoscopy and biopsy of lesions observed.

Material and Method: 701 upper gastro-intestinal biopsies were received and 283 were benign in three years study. The tissue was routinely processed and stained with hematoxylin and eosin.

Results and Conclusion: Majority of biopsies were gastric. Interesting lesions were - eosinophilic gastritis without parasitic infestation or eosinophilia; trichuris trichura in stomach; adult pyloric stenosis, fundic gland polyp with parietal cell hyperplasia in omeprazole user, ampullary heterotopic pancreas and duodenal ankylostomiasis. When compared with indian and western literature, this study too proves that endoscopic biopsy is useful in diagnosis, reducing surgeries.


Keywords

Benign Upper Gastro Intestinal Lesions, Endoscopic Biopsy, Interesting Pathologies
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  • William S. Haubrich , James M. Edmonson : Chapter 1 History of Endoscopy: Principles and concepts of gastroenterologic endoscopy: 2-15
  • Hopkins H H: Optical principles of endoscope. In Berci G Ed Endoscopy Ed.2 New York Appleton-Centary-Croft 1976:3-26
  • Practical Gastrointestinal Endoscopy: The Fundamentals: Peter B Cotton and Christopher B Williams 5th edition: Chapter 2 Equipment : 6-25
  • Colour Atlas of differential diagnosis in Exfoliative and Aspiration cytopathology: By Sudha R Kini; Chapter Eight Alimentary Tract- Esophagus/Gastrointestinal Tract and Biliary Tract:171-177
  • Ricardo H. Bardales, Michael W. Stanley, Donald D. Simpson, Sandra J. Baker, Cindy T. Steele, Robert F. Schaefer and Celeste N. Powers: Diagnostic value of brush cytology in the diagnosis of duodenal, biliary and ampullary neoplasms: American Journal of Clinical Pathology May 1998:109;5:540-548
  • Anderson’s Pathology (Tenth edition)-Ivan Damjanor and James Linder Vol.2:Chapter 53- Stomach and Duodenum:1661-1707
  • Anderson’s Pathology (Tenth edition)-Ivan Damjanor and James Linder Vol.2:Chapter 52- Esophagus:1647-1660
  • Kaiyo Takubo, Koji Sasajima, Kiyohiko Yamashita, Yoichi Tanaka, and Kichishiro Fujita: Double Muscularis Mucosae in Barrett’s esophagus : Human pathology 1991;22;1158-1161
  • David B. Skinner, Bruno C. Walther, Robert H. Riddell, Helmut Schmidt, Clement Iascone , Thomas R Demeester: Barrett’s Esophagus- Comparison of Benign and Malignant Cases: Annual Surgery Oct 1983;198;4:554-564
  • Punia RS, Arya S, Mohan H, Duseja A, Bal A; Spectrum of clinico-pathological changes in Barrett oesophagus: J Assoc Physicians India. 2006 Mar;54:187-189.
  • W. Rumfield, D. Jenkins, and B.B Scott: Unexpected gastro - esophageal candidiasis - an endoscopic survey : The British society of Gastroenterology : Gut 1980;21;A895
  • Sternberg’s Diagnostic Surgical Pathology (Fourth edition) Stacey. E. Mills, Darryl Carter, Joel K. Greenson, Harold. A. Oberman, Victor Reuter, Mar. H. Stoler Vol.2:Chapter 31- Esophagus:1399-1434
  • Nikhil Moorchung, A N Srivastava, N K Gupta, BR Achyut, Balraj Mittal: The histopathology of chronic gastritis: Indian Journal of Pathology and Microbiology 2007;50;1:18-24
  • Saeed Afzal, Mumtaz Ahmad, Azhar Mubarik, Farrukh Saeed, Shahid Rafi, Nasir Saleem, Ayaz Hussain Qur ;MORPHOLOGICAL SPECTRUM OF GASTRIC LESIONS - ENDOSCOPIC BIOPSY FINDINGS ;Pakistan Armed forces medical journal June 2006: 2
  • Piyalee Gupta, L B Pandey, R N Behra, M K Rai, R. Chandera: Role of ELISA in H. pylori detection and its correlation with urease test: Indian Journal of Pathology and Microbiology 2003;46;3:511-514
  • Vijaya V. Mysorekar, Chitralekha P Dandekar, BS Satya Prakash, Abhijit Sarkar: Role of imprint cytology in the diagnosis of gastrointestinal tract malignancies: Indian Journal of Pathology and Microbiology 2003;46;1:37-43
  • Sternberg’s Diagnostic Surgical Pathology (Fourth edition) Stacey. E. Mills, Darryl Carter, Joel K. Greenson, Harold. A. Oberman, Victor Reuter, Mar. H. Stoler Vol.2:Chapter 32 Stomach -:1435-1474
  • Thida Lwin, Shelby D Melton , Robert M Genta: Eosinophilic gastritis: histopathological characterization and quantification of the normal gastric eosinophil content: Modern Pathology 17 December 2010
  • Farhad Navab, Martin S. Kleinman, Kenneth Algazy., Eric Schenk., Michael D. Turner: Endoscopic diagnosis of eosinophilic gastritis : Gastrointestinal Endoscopy Nov 1972;19;2: 67-69.
  • Hong S T, Lim H S, Kim D H, Kim S J : A case of gastroenteritis associated with gastric trichuriasis: J Korean Med Sci. Jun 2003;18;3:429-432.
  • Alireza Zarineh, Marino E. Leon, Reda S. Saad, and Jan F. Silverman: Idiopathic Hypertrophic Pyloric Stenosis in an Adult, a Potential Mimic of Gastric Carcinoma- Case Report: Pathology Research International : 2010: Article ID 614280, 4 pages
  • Susan C. Abrahim, Vikesh K. Singh, John H. Yardley and Tsung The Wu: Hyperplastic polyps of the stomach-Associations with histologic patterns of gastritis and gastric atrophy: American Journal of Surgical Pathology 2001;25;4;500-507.
  • Enrico-G. Cristallini, Stefano Ascani, Giovanni B. Bolis: Association between histologic type of polyp and carcinoma in the stomach: Gastrointestinal Endoscopy 1992; 38; 481-484.
  • Takuji Nakamura, Gen-Ichi Nakano: Histopathological classification and malignant change in gastric polyp: Journal of Clinical Pathology Feb 1985: 754-764.
  • David J. Bjorkman et al : Proton-Pump Inhibitors and Fundic-Gland Polyps : Journal Watch Gastroenterology February 23, 2007.
  • Paolo Declich, Maria Sironi : Fundic gland polyps-An innocuous curiosity possibly with important pathological associations: Human Pathology Nov 1997;28;11:1328
  • Patrick L. Fitzgobbons, Cornelius P. Dooley, Hartley Cohen and Maria D. Appleman: Prevalence of gastric metaplasia, inflammation and Campylobacter pylori in the duodenum of members of a normal population: American Journal of Clinical Pathology 1988;90;6:711-714.
  • Mohamed, A. E.; Ghandour, Z. M.; Al-Karawi, M. A.; Yasawy, M. I.; Sammak, B.:Gastrointestinal parasites presentations and histological diagnosis from endoscopic biopsies and surgical specimens; Saudi Medical Journal 2000;21; 7; 629-634.
  • Sang Soo Shin, Yong Yeon Jeong and Heoung Keun Kang ; Giant Heterotopic Pancreas in the Jejunal Mesentery- Case Report : AJR 2007; 189:W262-W26.
  • Zhou Yuan, Jie Chen, Qi Zheng, Xin-Yu Huang, Zhe Yang, Juan Tang: Heterotopic pancreas in the gastrointestinal tract -CASE REPORT: WORld J of Gastroenterology 2009; Aug 7;15;29: 3701-3703.
  • Atindriya Biswas, Ehab A Husain, Roger M Feakins, Ajit T Abraham: Heterotopic Pancreas Mimicking Cholangiocarcinoma- Case Report and Literature Review: JOP. J Pancreas (Online) 2007; 8(1):28-34.
  • Hong Liu, Lisa R. Dixon, and Thomas J. George; Pancreatic Heterotopia Masquerading as Duodenal Carcinoid Gastrointest; Cancer Res. 2009 May–Jun; 3; 3: 118–120.
  • Giovanni Cammarota, Paolo Fedeli and Antonio Gasbarrini : Emerging technologies in upper gastrointestinal endoscopy and celiac disease : Gastroenterology & Hepatology 47 ;Jan 2009 :6:1.

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  • Spectrum of Benign Upper Gastro Intestinal Lesions Diagnosed by Endoscopic Examination Followed by Biopsy

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Authors

Trupti V Katti
Dept of Pathology, Navodaya Medical College (NMC), Raichur, Karnataka, India
Avril Dias
Dept. of Pathology, Goa Medical College (GMC), Bambolim, Goa, India
R G W Pinto
Dept. of Pathology, GMC, Bambolim, Goa, India

Abstract


Background: Upper gastrointestinal lesions run the gamut from inflammatory lesions to carcinoma. Endoscopy has greatly facilitated biopsy diagnosis. Present study reveals spectrum of benign upper gastro intestinal lesions obtained by endoscopic biopsy.

Aims:

1) To study types of lesions

2) Comparison with Indian and Western literature.

Setting & Design: It is observational study. Patients with upper gastro-intestinal complaints were subjected to endoscopy and biopsy of lesions observed.

Material and Method: 701 upper gastro-intestinal biopsies were received and 283 were benign in three years study. The tissue was routinely processed and stained with hematoxylin and eosin.

Results and Conclusion: Majority of biopsies were gastric. Interesting lesions were - eosinophilic gastritis without parasitic infestation or eosinophilia; trichuris trichura in stomach; adult pyloric stenosis, fundic gland polyp with parietal cell hyperplasia in omeprazole user, ampullary heterotopic pancreas and duodenal ankylostomiasis. When compared with indian and western literature, this study too proves that endoscopic biopsy is useful in diagnosis, reducing surgeries.


Keywords


Benign Upper Gastro Intestinal Lesions, Endoscopic Biopsy, Interesting Pathologies

References