Indian Journal of Public Health Research & Development

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Revascularization & Regenerative Endodontics: a Review of Current Status


Affiliations
1 Department of Conservative Dentistry, SPPGIDMS Lucknow, India
2 Department of Conservative Dentistry, UPDC & RC Lucknow, India
3 Department of Periodontics SPPGIDMS Lucknow, India
     

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Revascularization is a surgical procedure for the provision of a new, additional, or augmented blood supply to a body part or organ. Regenerative endodontics is the creation and delivery of tissues to replace diseased, missing, and traumatized pulp. This review provides an overview of revascularization and regenerative endodontics and its goals, the origin of stem cells, their properties, characteristics, current research, and their potential applications. The potential approaches include ischolar_main-canal revascularization, postnatal (adult) stem cell therapy, pulp implant, scaffold implant, three-dimensional cell printing, injectable scaffolds, and gene therapy. These regenerative endodontic techniques will possibly involve some combination of disinfection or debridement of infected ischolar_main canal systems with apical enlargement to permit revascularization and use of adult stem cells, scaffolds, and growth factors. Tissue engineering therapy offers the possibility of restoring natural function instead of surgical placement of an artificial prosthesis.

Keywords

Pulp Regeneration, Scaffolds, Stem Cell, Growth Factors, Tissue Engineering
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  • Revascularization & Regenerative Endodontics: a Review of Current Status

Abstract Views: 350  |  PDF Views: 0

Authors

Praveen Singh Samant
Department of Conservative Dentistry, SPPGIDMS Lucknow, India
Tanu Tewari
Department of Conservative Dentistry, UPDC & RC Lucknow, India
K. K. Gupta
Department of Periodontics SPPGIDMS Lucknow, India

Abstract


Revascularization is a surgical procedure for the provision of a new, additional, or augmented blood supply to a body part or organ. Regenerative endodontics is the creation and delivery of tissues to replace diseased, missing, and traumatized pulp. This review provides an overview of revascularization and regenerative endodontics and its goals, the origin of stem cells, their properties, characteristics, current research, and their potential applications. The potential approaches include ischolar_main-canal revascularization, postnatal (adult) stem cell therapy, pulp implant, scaffold implant, three-dimensional cell printing, injectable scaffolds, and gene therapy. These regenerative endodontic techniques will possibly involve some combination of disinfection or debridement of infected ischolar_main canal systems with apical enlargement to permit revascularization and use of adult stem cells, scaffolds, and growth factors. Tissue engineering therapy offers the possibility of restoring natural function instead of surgical placement of an artificial prosthesis.

Keywords


Pulp Regeneration, Scaffolds, Stem Cell, Growth Factors, Tissue Engineering

References