![Open Access](https://i-scholar.in/lib/pkp/templates/images/icons/fulltextgreen.png)
![Restricted Access](https://i-scholar.in/lib/pkp/templates/images/icons/fulltextred.png)
![Open Access](https://i-scholar.in/lib/pkp/templates/images/icons/fulltextgreen.png)
![Open Access](https://i-scholar.in/lib/pkp/templates/images/icons/fulltext_open_medium.gif)
![Restricted Access](https://i-scholar.in/lib/pkp/templates/images/icons/fulltextred.png)
![Restricted Access](https://i-scholar.in/lib/pkp/templates/images/icons/fulltext_restricted_medium.gif)
Distribution of Blood Groups among Patients with Diabetes Mellitus and their Secretor Status
Subscribe/Renew Journal
Variety of diseases has been studied in relation to ABO blood groups and secretor status of blood group antigens. There is ample justification for probing into relation between blood groups, secretor status and diabetes mellitus because genetic, environmental factors etc. play important role in etiology of diabetes mellitus. Number of workers have tried to study the relationship between diabetes mellitus, secretor status and blood groups, but results have been variable. Although some workers have found definite preponderance of particular blood group, it has been concluded that so far no convincing association between blood groups, secretor status and diabetes mellitus has been established. There are few studies involving Indian origin on distribution of blood groups and secretor status among patients with diabetes mellitus. Therefore, distribution of blood groups (ABO) and secretor status were studied in 105 diabetic patients and compared with age and sex matched normal healthy controls. Only confirmed diabetic patients were included in this study. Blood group was determined by slide agglutination method. Secretor status was determined by haemagglutination inhibition technique using saliva. The study showed no statistically significant correlation in distribution of blood groups (ABO) and secretor status among diabetics as compared to controls.
Keywords
ABO Blood Group, Secretor Status, Haemagglutination Inhibition Technique, Saliva, Diabetes Mellitus
Subscription
Login to verify subscription
User
Font Size
Information
- Gupta YN, Gupta S, Sanyal B. Blood group specific substances in saliva of patients with cervical carcinoma. Int J Gynaecol obstet 1981; 19:83-84.
- Tandon OP, Bhatia S, Tripathi RL. Phagocytic response of leucocytes in secretors and non secretors of ABH (O) blood group substances. Ind. J Physiol. Pharmac 1979; 23(4):321-324.
- Patick AW, Collier A. An Infectious etiology of insulin dependent diabetes mellitus? Role of the secretor status. FEMS Microbial Immunol 1989; 1 (6-7):411-416.
- Saudicani P, Hein HO, Gyntelberg F. Genetic and life style determinants of peptic ulcer. A study of 3387 men aged 54 to 74 years. The Coppenhagen Male study, Scand J Gastroenterol 1999; 34:12-17.
- Raza MW, Balckwell CC, Molyneaux P. Association between secretor status and respiratory viral illness. BMJ 1959;1: 603-607.
- Diabetes Mellitus.Report of WHO Study Group, Geneva, Switzerland. WHO technical Report series 1985; No: 727.
- Godkar PB, Godkar DB. Text book of medical laboratory technology. 2nd edn.2003.Mumbai. Bhalani Publishing House: pp 860-865.
- Roy MN, Chatterjee JB. Some observations on secretion the secretions on the secretion of blood group substances in the body fluids of man. J.Ind.Med.Ass 1965; 45:413-417.
- Trinder P .GOD-POD Methodology. Ann.Clin.Biochem 1969; 6: 24.
- Saran RK, Makroo RN. Transfusion medicine technical manual 1991. Directorate General of Health Services, New Delhi, a ‘n’ b communications Private Limited :pp 50.
- Buchanan JA and Higley ET . Relationship of blood groups to disease. Brit.J.Exper path 1921; 2:247-255.
- Aird I, Bentall H, Mehigan JA. Blood groups in relation to peptic ulceration and carcinomes of colon, rectum, breast and bronchus. BMJ 1954; 2:315-321.
- Buckwalter JA, Wohlwend EB, Colter DC. ABO blood groups and disease. JAMA 1956; 162(13):1210-1215.
- Camerson JM. Blood groups in tumors of salivary tissues. Lancet 1958; 1:239-240.
- Salzono FM. Blood group and Leprosy. J.Med. Genet 1967;4: 102-106.
- Mc Connel RB, Pyke DA . Blood group in diabetes mellitus. BMJ 1956; 1:772-776.
- Macafee AL. Blood groups and diabetes mellitus. J.Clin Path 1964; 17:39-41.
- Sidhu, LS, Malhotra P and Singh SP. ABO and Rh blood groups in diabetes mellitus. Anthropol. Anz 1988; 46:
- Iyengar, S., Hamman, R.F, Marshall, J.A, Baxter, J, Majumder, P.P. and Ferrell, R.E. Genetic Studies of type 2 (non –insulin dependent) diabetes mellitus: Lack of association with seven genetic markers. Diabetologia1989; 32: 690-693.
- Qureshia, M.A. and Bhatti, R. Frequency of ABO blood groups among the diabetes mellitus type 2 patients. Coll. Physicians Surg. Pak 2003; 13: 453-455.
- Jolly JG, Sarup, Aikat BK. Diabetes mellitus and Blood groups. J. Indian Med. Ass 1969; 52: 104- 107.
- Buckwalter JA. Diabetes and blood groups. Diabetes 1964; 13(2):164-168.
- Doll R, Drane H, Newell AC. Secretion of blood group substances in duodenal, gastric and stomal ulcer, gastric carcinoma and diabetes mellitus. Gut 1961; 2:352-359.
- Peters WH, Gohler W.ABH secretion and Lewis red cell groups in diabetics and normal subjects from Ethopia. Exp Clin Endocrinol 1986; 88(1):64-70.
- Eff C, Faber O, Deckert T. Persistent insulin secretion, assessed by plasma C peptide estimation in long term juvenile diabetics with a low insulin reuirement.Diabetologia 1978;15(3):169-172.
- Blackwell CC, Weir DM, Patric AW. Secretor state and Complement levels (C3 and C4) in Insulin dependent diabetes mellitus. Diabetes Res 1988; 9(3):117-119.
![](https://i-scholar.in/public/site/images/abstractview.png)
Abstract Views: 337
![](https://i-scholar.in/public/site/images/pdfview.png)
PDF Views: 0