Indian Journal of Public Health Research & Development

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Prenatal Histogenesis of Human Spleen


Affiliations
1 RIMS Medical College, Kadapa-516002, A.P., India
     

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Human spleen is an organ of anatomic and functional component of reticuloendothelial system. Spleen is situated in left hypochondrial region. It is soft friable, highly vascular and dark purple in colour. Histogenesis of spleen Studied in 50 fetuses of various gestational ages ranging from 11weeks to 38weeks.

By 11th week only lymphocytic aggregation seen.

By 20th week developing lymphoid follicles observed.

By 32 weeks well developed lymphoid follicles with central arteriole seen.

At 36 weeks crack at periphery of developing lymphoid follicles and arteriole is at periphery.


Keywords

Lymphoid Aggregation, Lymphoid Follicles, Central Arteriole, Histogenesis, White Pulp
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  • Hamilton J, Mossman H.W; Hamilton’s Boyd and Mossman’s Human Embryology, Prenatal development of respiratory system. 4th Edn.1966, pp 363-364.

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  • Vellguth.S, et al. The development of the human spleen, Ultra structural studies in fetuses from the 14th to 24th week of gestation. Cell and Tissue Res.1985; 242(3): 579-92.


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  • Prenatal Histogenesis of Human Spleen

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Authors

D. Radhika
RIMS Medical College, Kadapa-516002, A.P., India
N. Saila Rekha
RIMS Medical College, Kadapa-516002, A.P., India
G. Kanchanalatha
RIMS Medical College, Kadapa-516002, A.P., India
K. V. Murali Mohan
RIMS Medical College, Kadapa-516002, A.P., India
L. Anandakumar
RIMS Medical College, Kadapa-516002, A.P., India
N. Mary Hemiliamma
RIMS Medical College, Kadapa-516002, A.P., India

Abstract


Human spleen is an organ of anatomic and functional component of reticuloendothelial system. Spleen is situated in left hypochondrial region. It is soft friable, highly vascular and dark purple in colour. Histogenesis of spleen Studied in 50 fetuses of various gestational ages ranging from 11weeks to 38weeks.

By 11th week only lymphocytic aggregation seen.

By 20th week developing lymphoid follicles observed.

By 32 weeks well developed lymphoid follicles with central arteriole seen.

At 36 weeks crack at periphery of developing lymphoid follicles and arteriole is at periphery.


Keywords


Lymphoid Aggregation, Lymphoid Follicles, Central Arteriole, Histogenesis, White Pulp

References