Indian Journal of Public Health Research & Development

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Fibrosarcoma in the Mandible - a Rare Case Report


Affiliations
1 Department of Pathology, Hassan Institute of Medical Sciences, Hassan, Karnataka, India
2 Department of Oral Surgery, N.S.V.K. Sri Venkateshwara Dental College and Hospital, Bangalore, Karnataka, India
3 Department of Oral Pathology, S.J.M. Dental College and Hospital, Chitradurga, Karnataka, India
     

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Fibrosarcoma is a malignant neoplasm of the fibroblastic origin. It can occur in any location being the bone extremities the main affected site. Fibrosarcoma in relation to the orofacial region are rare. Occurrences in the mandible are rare with an incidence ranging from 0 to 6.1% of all primary fibrosarcoma of the bone. Radical surgery seems to be the best treatment option to fibrosarcoma. Radiation therapy has been used as adjuvant treatment in unresectable tumors and chemotherapy is only used for palliative treatment. Here is a case of fibrosarcoma in the right posterior mandible in 62 year old man.

Keywords

Fibrosarcoma, Tumor, Mesenchymal, Orofacial Region, Mandible
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  • Neville, Damm, Allen, Bouquot (2002). Oral and Maxillofacial Pathology, 2nd edition.

  • Robert E. Marx, Diane Stern (2003). Oral and Maxillofacial Pathology, a rationale for diagnosis and treatment.

  • Shafer, Hine, Levy (2006). Shafer’s textbook of Oral Pathology, 5th edition.

  • M J Egan, F Raafat, J Crocker, K Smith. Nucleolar organiser regions in fibrous proliferations of childhood and infantile fibrosarcoma. J Clin Pathol 1988; 41:31-33.

  • Mark RJ, Sercarz JA, Tran L, Selch M, Calcaterra TC. Fibrosarcoma of the Head and Neck. The UCLA experience. Arch Otolaryngol Head Neck Surg 1991; 117:396-401.

  • Frankenthaler R, Ayala A, Hartwick R, Goepfert H: Fibrosarcoma of the head and neck. Laryngoscope 100:799–802, 1990

  • Doughlass Gnepp. Surgical Pathology of head and neck.

  • Taconis, W.K. and T.G. van Rijssel, Fibrosarcoma of long bones A study of the significance of areas of malignant fibrous histiocytoma. J Bone Joint Surg Br, 1985.

  • A L Eyre-Brook. A Bone Tumour Registry - Chondrosarcoma and Fibrosarcoma of Bone. Volume 54 July 1961.

  • Norman Poole, J. D. Palmer, and W. H. Mathews. Soft tissue fibrosarcoma. Canad. M. A. J. July 1, 1961, vol. 85.

  • Conley J, Stout A, Healey W: Clinicopathologic analysis of eighty four patients with an original diagnosis of fibrosarcoma of the head and neck. Am J Surg 114: 564–569, 1967

  • Sessions D, Ogura J: Fibrosarcoma of the head and neck: a clinical analysis of forty cases. Ann Otol 83: 439–444, 1974

  • Wanebo H, Koness R, McFarlane J, Eilber F, Byers R, Elias E, Spiro R: Head and neck sarcoma: Report of the head and neck sarcoma registry. Head Neck 14: 1–7, 1992

  • Odell P: Head and neck sarcomas: a review. Otolaryngology 25: 7–13, 1996

  • Cecchetto G, Carli M, Alaggio R, Dall’igna P, Bisogno G, Scarzello G, Zanetti I, Durante G, Inserra A, Siracusa F, Guglielmi M: Fibrosarcoma in pediatric patients: results of the Italian cooperative group studies (1979–1995). J Surg Oncol 78: 225– 235, 2001

  • Suit H, Mankin H, Wood W: Preoperative, intraoperative and postoperative radiation in the treatment of primary soft tissue sarcoma. Cancer 55: 2659–2667, 1985

  • Slater J, McNeese M, Peters L: Radiation therapy for unresectable soft tissue sarcoma. Int J Radiat Oncol Biol Phys 12: 1729–1734, 1986

  • Greager J, Reichard K, Campana J: Fibrosarcoma of the head and neck. Am J Surg 52: 437–439, 1994

  • Miser J, Triche T, Kinsella T: Other soft tissue sarcomas in children. In: Pizzo PA, Poplack DG (eds.), Principles and practice of Pediatric Oncology, 3rd edition. Philadelphia: Lippincott- Raven, 873–876, 1997 [Chapter 32]

  • Das Gupta T, Patel M, Chaudhuri P: The role of chemotherapy as an adjuvant to surgery in the initial treatment of primary soft tissue sarcomas in adults. J Surg Oncol 19: 139–144, 1982

  • Rosenberg S, Tepper J, Glatstein E: Prospective randomized evaluation of adjuvant chemotherapy in adults with soft tissue sarcomas of the extremities. Cancer 52: 424–434, 1983

  • Antman KH: Adjuvant therapy of sarcomas of soft tissue. Semin Oncol 24: 556–560, 1997

  • Scurr M, Judson I: Neoadjuvant and adjuvant therapy for extremity soft tissue sarcomas. Hematol Oncol Clin North Am 19: 489–500, 2005

  • W Gu, A Ogose, H Kawashima, H Umezu, N Kudo, T Hotta, N Endo. Congenital dermatofibrosarcoma protuberans with fibrosarcomatous and myxoid change. J Clin Pathol 2005; 58:984–986.

  • Swain RE, Sessions DG, Ogura JH: Fibrosarcoma of the head and neck: a clinical analysis of forty cases. Ann Otol RhinoLaryngol 83: 439–444, 1974

  • Weber R, Benjamin R, Peters L, Ro J, Achon O, Goepfert H: Soft tissue sarcomas of the head and neck in adolescents and adults.Am Surg 152: 386–392, 1986.

  • Rabindra P. Singh et al. Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome. Hindawi Publishing Corporation Sarcoma Volume 2008, Article ID 654987, 5 pages. 74–83.

  • Harvey E L Teo and Wilfred C G Peh. Primary bone tumors of adulthood. Cancer Imaging (2004) 4.


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  • Fibrosarcoma in the Mandible - a Rare Case Report

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Authors

P. M. Vijay
Department of Pathology, Hassan Institute of Medical Sciences, Hassan, Karnataka, India
N. S. Kedarnath
Department of Oral Surgery, N.S.V.K. Sri Venkateshwara Dental College and Hospital, Bangalore, Karnataka, India
V. M. Sudha
Department of Oral Pathology, S.J.M. Dental College and Hospital, Chitradurga, Karnataka, India
Chandrashekarraju
Department of Oral Pathology, S.J.M. Dental College and Hospital, Chitradurga, Karnataka, India

Abstract


Fibrosarcoma is a malignant neoplasm of the fibroblastic origin. It can occur in any location being the bone extremities the main affected site. Fibrosarcoma in relation to the orofacial region are rare. Occurrences in the mandible are rare with an incidence ranging from 0 to 6.1% of all primary fibrosarcoma of the bone. Radical surgery seems to be the best treatment option to fibrosarcoma. Radiation therapy has been used as adjuvant treatment in unresectable tumors and chemotherapy is only used for palliative treatment. Here is a case of fibrosarcoma in the right posterior mandible in 62 year old man.

Keywords


Fibrosarcoma, Tumor, Mesenchymal, Orofacial Region, Mandible

References